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Last Updated 08/12/18
   

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Kidney transplants are the second most common transplant operation in the United States (over 16,500 cases per year - cornea transplants are first). Compared to heart, lung, or liver transplants, it is an easier and less complicated operation.

The United Network for Organ Sharing (UNOS) is the private organization that runs the US transplant system under a contract with the federal government.

Despite continuing advances in medicine and technology, the demand for kidneys drastically outstrips the number of donors. In 2013, there were over 96,000 persons on waiting lists for kidney transplants in the US.

There are two types of kidney transplantation: cadaveric and living donor. Cadaver organs are distributed to those on a waiting list based on criteria set forth by UNOS. Live donor transplantation has become increasingly common, due in large part to the success of the procedure and the shortage of cadaveric organs. Living donation allows the immediate transplantation of kidneys into recipients so operations can be scheduled electively once a suitable living donor has been identified. This avoids the long waiting times encountered with cadaveric donation. A new procedure, the laparoscopic nephrectomy, has greatly reduced the trauma and recovery period for a living donor.

Kidney transplant recipients usually must take immunosuppressants, or anti-rejection drugs, for the rest of their lives. Medicare coverage for these medications is currently limited to three years, but federal legislation has been introduced to extend coverage. Immunosuppressant medications run on average between $1,000 - $1,200 monthly.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Renal Allograft Survival Rates in Kidneys Initially Declined for Pediatric Transplantation - Free, Open Access Article from Pediatric Nephrology. - September 2018

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Free, Full-Text Articles from American Journal of Transplantation - August 2018

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Free, Full-Text Articles from Transplantation - August 2018

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Kidney Transplant Chains More Effective in Saving Lives - Press release from University of British Columbia — Sauder School of Business. - August 9, 2018

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Medication Adherence Is Associated with an Increased Risk of Cancer in Kidney Transplant Recipients: a Cohort Study - Advance Articles Abstract from NDT. - August 8, 2018

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Celebrating Zero Days of Dialysis One-Year Post-Transplant - Article from Dialysis Clinics, Inc. - August 2018

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Polygenic Risk Score As a Determinant of Risk of Non-Melanoma Skin Cancer in a European-Descent Renal Transplant Cohort - Accepted Article abstract from American Journal of Transplantation. - August 7, 2018

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New Agent Allows Kidney Transplantation Despite High-Strength Donor-Specific Antibody - (Registration required, but free.) Article from Reuters Health via Medscape Nephrology. - August 7, 2018

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Helping More Patients Receive a Living Donor Kidney Transplant - CJASN Express abstract. - August 6, 2018

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Opt-Out Organ Donation 'in Place by 2020' for England - Article from the BBC. - August 5, 2018

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Influence of Pre-Transplant Midodrine Use on Outcomes after Kidney Transplantation - First Published abstract from Clinical Transplantation. - August 4, 2018

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Accepted Article Abstracts from American Journal of Transplantation - August 3, 2018

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Hepatitis C-infected Organs Safe for Transplantation When Followed by Antiviral Treatment - Press release from Penn Medicine. Latest Article abstract and editorial extract from Annals of Internal Medicine. Article from HealthDay. - August 3, 2018

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Mayo Clinic Minute: Being a Living Organ Donor Is Safer, Easier Than You Think - Article and video from the Mayo Clinic. - August 3, 2018

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After 15 years of Trying, Scientists Successfully Transplanted Lab-Grown Lungs into Pigs - Article from Quartz. - August 1, 2018

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Bioengineered Lungs Successfully Transplanted Into Pigs - Article from HealthDay. - August 1, 2018

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Minding the Missing Link – The Effect of Donor-Recipient Pairing on Kidney Transplant Outcomes - Free, full-text, CJASN Express article. - July 2018

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Survival and Kidney Transplant Incidence on Home Versus In-Center Hemodialysis, Following Peritoneal Dialysis Technique Failure - PDI in Press Abstract. - July 31, 2018

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Temporal Changes in the Composition of a Large Multicenter Kidney Exchange Clearinghouse: Do the Hard-to-Match Accumulate? - Accepted Article abstract from American Journal of Transplantation. - July 31, 2018

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Nation's Longest Single-Site Kidney Chain Reaches 100 - Press release from University of Alabama at Birmingham. - July 30, 2018

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Incidence of New-Onset Diabetes Mellitus and Association with Mortality in Childhood Solid Organ Transplant Recipients: a Population-based Study - Advance Article abstract from NDT. - July 30, 2018

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Population Level Outcomes and Cost-Effectiveness of Hepatitis C Treatment Pre-Versus Post Kidney Transplant - Accepted Article abstract from American Journal of Transplantation. - July 30, 2018

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Spain Leads the World in Organ Donation — What's Stopping Other Countries Catching Up? - Article from The Independent (UK). - July 29, 2018

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Interleukin-27 Is a Potential Marker for the Onset of Posttransplant Malignancies - Advance Article Abstract from NDT. - July 27, 2018

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Transplanted Kidney Survives Longer - Press release from KU Leuven. - July 24, 2018

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Transplantation of Hepatitis C Virus (HCV) Antibody Positive, Nucleic Acid Test Negative Donor Kidneys to HCV Negative Patients Frequently Results in Seroconversion but Not HCV Viremia - Accepted Article abstract from American Journal of Transplantation. - July 24, 2018

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Explore Transplant Ontario: Adapting the Explore Transplant Education Program to Facilitate Informed Decision Making About Kidney Transplantation - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - July 24, 2018

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HRSA Recognizes Hospitals for Organ Donation Efforts - News brief from American Hospital Association. - July 24, 2018

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Management of Chronic Renal Allograft Dysfunction and When to Re-Transplant - Free, Open Access, First Online educational review from Pediatric Nephrology. - July 23, 2018

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Analyses of the Short-and Long-Term Graft Survival after Kidney Transplantation in Europe between 1986 and 2015 - Article in Press abstract from Kidney International. - July 23, 2018

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When the Source of Inflammation Is Hiding in Plain Sight: Failed Kidney Transplants, Clotted Arteriovenous Grafts, and Central Venous Catheters - Early View Abstract from Seminars in Dialysis. - July 22, 2018

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The Evolution of Kidney Transplantation in HIV-Positive Patients - Posting from the AJKD blog. - July 20, 2018

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Albuminuria and Allograft Failure, Cardiovascular Disease Events, and All-Cause Death in Stable Kidney Transplant Recipients: A Cohort Analysis of the FAVORIT Trial - Articles in Press Abstract American Journal of Kidney Diseases. - July 20, 2018

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Iran Pays Kidney Donors. Should the U.S. Follow? - Article and video from PBS NewsHour. - July 19, 2018

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Restricting Who Gets an Organ Transplant - Article from Tufts Now. - July 19, 2018

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Vanderbilt Opens Telemedicine Clinic for Kidney Transplant Screening - Press release from Vanderbilt University Medical Center. - July 19, 2018

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Returning to Hemodialysis after Kidney Allograft Failure: a Survival Study with Propensity Score Matching - Advance Articles Abstract from NDT. - July 19, 2018

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Rethinking Regenerative Medicine From a Transplant Perspective (and Vice Versa) - Online First abstract from Transplantation. - July 18, 2018

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Dramatic Secular Changes in Prognosis for Kidney Transplant Candidates in the United States - Accepted Article abstract from American Journal of Transplantation. - July 18, 2018

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Determinants of Organ Donation Registration - Accepted Article abstract from American Journal of Transplantation. - July 18, 2018

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Organ Donation and the Principles of Gift Law - Free, Full-Text, CJASN Express Article. - July 17, 2018

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Case Mix, Patterns of Care, and Inpatient Outcomes Among Ontario Kidney Transplant Centers: A Population-Based Study - Free, Open Access Article from Canadian Journal of Kidney Health and Disease. - July 17, 2018

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UCLA Led the Nation in Organ Transplants in 2017 - Press release. - July 16, 2018

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ABO-Incompatible Kidney Transplant Outcomes — A Meta-Analysis - CJASN Express abstract. - July 16, 2018

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Significantly Lower Rates of Kidney Transplantation among Candidates Listed with the Veterans Administration: A National and Local Comparison - JASN Express Abstract. - July 13, 2018

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Delayed Graft Function: The AKI of Kidney Transplantation - Free, full-text, Online First article from Nephron. - July 13, 2018

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How To Better Enable Kidney Exchanges To Improve Health and Save Money - Article from Stanford Engineering. - July 11, 2018

blue ball Latest transplant news from the United Network for Organ Sharing (UNOS)
blue ball Kidney Transplant news stories from Yahoo! News - Continually Updated!
 
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  ANTI-REJECTION DRUG INFORMATION

blue ball Azathioprine ("Imuran") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for azathioprine and kidney transplant Continually Updated!
Corticosteroids ("Prednisone" and many others) - Drug Info from The MedMaster™ Patient Drug Information database. National Library of Medicine PubMED search results for corticosteroids and kidney transplant Continually Updated! Search results for prednisone Continually Updated!
Cyclosporine ("Sandimmune" or "Neoral") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for cyclosporine and kidney transplant Continually Updated!
Mycophenolate ("CellCept") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for mycophenolate and kidney transplant Continually Updated!
blue ball Pycnogenol ("Zenapax®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for daclizumab and kidney transplant Continually Updated!
Sirolimus ("Rapamune®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for sirolimus and kidney transplant Continually Updated!
Tacrolimus ("Prograf" or FK506) - Drug Info from Medline Plus. National Library of Medicine PubMED search results for tacrolimus and kidney transplant Continually Updated!
 

  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Kidney Transplantation
blue ball Alliance for Paired Donation web site
Bienvenido a Infórmate - kidney transplantation information for Hispanic/Latino patients from the National Kidney Foundation
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Booklet Advises Parents of Pediatric Transplant Patients - Resource (35-page pdf) from UNOS Transplant Living. - 2018

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Brochure Addresses Patients' Questions about Transplant Candidate Kidney Evaluation and Listing - PDF Resource from the United Network for Organ Sharing

Center and OPO Specific Reports from the Scientific Registry of Transplant Recipients web site
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Evaluation of Kidney Donors: Core Curriculum 2018 - Free, Full-Text, Articles in Press from American Journal Of Kidney Disease - January 2018

Financial Assistance for Living Donors web site
The Gift that Heals: Stories of hope, renewal and transformation through organ and tissue donation - book by Reg Green
Guidelines for Preventing Transmission of Human Immunodeficiency Virus Through Transplantation of Human Tissue and Organs from the CDC - May 20, 1994
Help Hope Live web site
How the Transplant Waiting List Works - Article from the Renal Support Network - April 2012
blue ball Hundreds of Interlaced Fingers: A Kidney Doctor's Search for the Perfect Match - A young, hopeful doctor's memoir (book) --an unforgettable love story and an informative journey into the world of medicine and kidney transplantation that ultimately asks: What does it mean to let go of something that you love, even if it is life itself?

The Jewish Kidney & Transplant Support Center - Advice and support for kidney transplant and dialysis patients

Kidney/Pancreas Transplant Program from the Johns Hopkins Medical Institutions
Kidney Transplant  web sites from Yahoo!
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Kidney Transplant eBook - by Dr. Leonardo V. Riella - September 2016

Living Kidney Donor Network
Living Kidney Donor Search
Living Kidney Donor Search Tools and Tips web site
Living Donors Online Message Board discussion page
Medical Complications of Kidney Transplantation (Hardcover) by Claudio Ponticelli (Editor) - January 2008
National Donor Memorial web site
National Foundation for Transplants web site
National Kidney Registry web site
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National Living Donor Assistance Center - Website developed by Transplant Informatics Institute, a subsidiary of UNOS.

National Service Framework for Renal Services: Part One - Dialysis and transplantation - Department of Health web site

Organ Donation Toolbox - from the Organ Donation and Transplantation Alliance web site

Organdonor.gov video explains donation, transplantation processes

The Organ Procurement and Transplantation Network (OPTN) weekly updated Waiting Lists for transplants.
blue ball OPTN / SRTR 2016 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
Organ Transplant from the University of Southern California web site
Pediatric Transplantation web site
Pregnancy After Transplant from the Transplant Living web site
Influenza and Transplant Recipients: Ways To Prevent And Treat - Conversations in Transplantation from the American Society of Transplantation - November 2010
Q&A on Living Donation from the NKF web site
Questions About Kidney Transplantation from TransWeb.org web site
blue ball Renal Transplantation - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
The Scientific Registry of Transplant Recipients (SRTR) web site.
Top 10 Myths About Donation & Transplantation from TransWeb.org web site
Transplantation and Organ and Tissue Donors and Transplant Recipients from the NKF web site.
TransplantLiving - the patient's connection to the transplant community from UNOS
Update: Investigations of West Nile Virus Infections in Recipients of Organ Transplantation and Blood Transfusion - from MMWR - September 20, 2002
UNOS Corporate Annual Report from the United Network for Organ Sharing (UNOS)
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UNOS Transplant Pro - website for transplant professionals

blue ball What Every Parent Needs to Know - booklet advises parents of pediatric transplant patients produced by the OPTN/UNOS Patient Affairs Committee
Who is Eligible for Medicare? from the The Official U.S. Government Site for Medicare Information
 
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  ESSENTIALS AND CLASSICS

blue ball Evaluation of Kidney Donors: Core Curriculum 2018 from the American Journal of Kidney Disease
blue ball Transplantation Fact Sheet (pdf) from the American Nephrology Nurses’ Association
European Best Practice Guideline for Transplantation Part 1 and European Best Practice Guideline for Transplantation Part 2 - guidelines endorsed by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA)
Treatment Methods for Kidney Failure: Kidney Transplantation from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
End-Stage Renal Disease: Choosing a Treatment That's Right for You: Transplantation from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
HLA Matching from the University of Michigan Medical Center.
 
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  KDIGO™ -  Kidney Disease: Improving Global Outcomes
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Kidney Disease Improving Global Outcomes (KDIGO) web site

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  PUBMED SEARCHES

kidney transplant Continually Updated!
organ donor and kidney Continually Updated!
renal transplant and HLA matching Continually Updated!
kidney transplant and complications Continually Updated!
kidney transplant and rejection Continually Updated!
 
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  LAPAROSCOPIC NEPHRECTOMY

Live Doner Laparoscopic Nephrectomy For Kidney Transplantation - article from the University of Southern California Kidney Transplant Program.

Here is a listing of articles on the laparoscopic nephrectomy procedure from the latest scientific journals (PubMed search).

 
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  NON-DIRECTED DONATION AND "SWAPS"

 
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  STATISTICS

blue ball U.S. Facts About Kidney Transplantation from the Organ Procurement and Transplantation Network (OPTN) web site
blue ball OPTN / SRTR 2016 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  UPCOMING EVENTS

blue ball Listing of North American Transplant Coordinators Organization (NATCO) Meetings
 
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  TRANSPLANT CENTERS

blue ball US Transplant Centers - from the OPTN web site
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  XENOTRANSPLANTATION, BIOTECH, AND STEM CELL RESEARCH

blue ball FDA Guidance for Industry on Xenotransplantation from the U.S. Food & Drug Administration
blue ball These two web sites provide opposing viewpoints on xenotransplantation. Here is the the International Xenotransplantation Association.
blue ball U.S. Public Health Service Guideline on Infectious Disease Issues in Xenotransplantation from the Morbidity & Mortality Weekly Report (MMWR) - August 24, 2001
blue ball Stem Cell Information - from the National Institutes of Health
blue ball Stem Cell Research - Full coverage page from Yahoo
blue ball Beyond Transplants: Growing Organs in the Lab from Popular Mechanics
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Interspecies Organogenesis-Derived Tissues for Transplantation - free, full-text articles from Transplantation - July 2017

blue ball 24-minute Video from The Kidney Project Facebook Page on their Implantable Artificial Kidney - This is a UCSF project headed by Shuvo Roy
 
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  DISCUSSION FORUM

blue ball General Nursing Discussion Forum - RenalWEB Discussion Forum
 
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  INPUT / SUGGESTIONS

blue ball E-mail to RenalWEB on the Transplantation Topic
 
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