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Last Updated 12/17/17
   

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Kidney transplants are the second most common transplant operation in the United States (over 16,500 cases per year - cornea transplants are first). Compared to heart, lung, or liver transplants, it is an easier and less complicated operation.

The United Network for Organ Sharing (UNOS) is the private organization that runs the US transplant system under a contract with the federal government.

Despite continuing advances in medicine and technology, the demand for kidneys drastically outstrips the number of donors. In 2013, there were over 96,000 persons on waiting lists for kidney transplants in the US.

There are two types of kidney transplantation: cadaveric and living donor. Cadaver organs are distributed to those on a waiting list based on criteria set forth by UNOS. Live donor transplantation has become increasingly common, due in large part to the success of the procedure and the shortage of cadaveric organs. Living donation allows the immediate transplantation of kidneys into recipients so operations can be scheduled electively once a suitable living donor has been identified. This avoids the long waiting times encountered with cadaveric donation. A new procedure, the laparoscopic nephrectomy, has greatly reduced the trauma and recovery period for a living donor.

Kidney transplant recipients usually must take immunosuppressants, or anti-rejection drugs, for the rest of their lives. Medicare coverage for these medications is currently limited to three years, but federal legislation has been introduced to extend coverage. Immunosuppressant medications run on average between $1,000 - $1,200 monthly.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Reflections on the Global Needs for Renal Transplantation - Article from The Lancet Kidney Campaign. - December 2017

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Free, Full-Text Articles from American Journal Of Kidney Diseases - December 2017

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Free, Full-Text Articles from American Journal of Transplantation - December 2017

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Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients - (Registration required, but free.) Free, full-text article from American Journal of Transplantation via Medscape Nephrology. - December 15, 2017

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Clinical Trial Does Not Support the Use of Bortezomib for Kidney Transplant Recipients - Press release from the American Society of Nephrology. - December 14, 2017

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India's Laws on Organ Transplants Do Little to Protect Rights of Organ Donors - Article from Scroll.in. - December 14, 2017

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Considering Tangible Benefit for Interdependent Donors - (Registration required, but free.) Free, full-text article from American Journal of Transplantation via Medscape Nurses. - December 13, 2017

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Organ Donor Research — Overcoming Challenges, Increasing Opportunities - Free, full-text, viewpoint article from the Journal of the American Medical Association. - December 12, 2017

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New Diagnosis of Bullous Pemphigoid after Withdrawal of Immunosuppressive Therapy in a Failed Renal Transplant Recipient on Hemodialysis - Early View Abstract from Hemodialysis International. - December 11, 2017

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Early View Abstracts from American Journal of Transplantation - December 9, 2017

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A Review of 1748 Kidney Paired Donation Transplants - (Registration required, but free.) Free, full-text article from American Journal of Transplantation via Medscape Nephrology. - December 8, 2017

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Long-Term Prevention of Organ Rejection - Press release from University of Konstanz. - December 8, 2017

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Many Donor Kidneys That Are Discarded May Be Suitable for Transplantation - Press release and CJASN Express abstract from the American Society of Nephrology. Article from HealthDay. - December 7, 2017

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Free, Full-Text Articles from the Clinical Journal of the American Society Of Nephrology - December 7, 2017

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Direct and Indirect Costs Incurred by Australian Living Kidney Donors - Accepted Article abstract from Nephrology. - December 7, 2017

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Our Medicare Policy for Kidney Transplants Is Totally Irrational - Opinion piece from The Washington Post. - December 6, 2017

Editor's note: The only explanation of this policy is the self-interest and lobbying power (campaign contributions) of large corporations with a stake in the dialysis industry. Who is the most influential CEO in the U.S. dialysis industry?

Combining junk-bond-financing and medicine... only makes bad medicine. Want an example? See this 2013 blog post on the legislation.

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Researchers 3-D Print Lifelike Artificial Organ Models - Press release from the University of Minnesota. - December 6, 2017

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Technology May Help Increase Number of Kidneys Transplanted - Press release and free, full-text, Early View article from British Journal of Surgery. - December 6, 2017

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Early View Abstracts from American Journal of Transplantation - December 5, 2017

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'Living Ink' Points the Way to 3D-Printed Human Organs - (Registration required) Article from Financial Times. - December 5, 2017

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3-D Printing Could Expand Medical Device Regulation: Here's How - Article from MassDevice. Statement by FDA Commissioner. - December 4, 2017

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In New Zealand, New Law Will See Organ Donors Compensated - Audio report and article from Newstalk ZB. Media releases from Kidney Health NZ. - December 4, 2017

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Urologic Malignancies in Kidney Transplantation - Early View abstract from American Journal of Transplantation. - December 1, 2017

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Scientists Create Successful Mass Production System for Bioengineered Livers - November 30, 2017

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Study Identifies Genes Involved in Tolerance Following Kidney Transplantation - Press release from the American Society of Nephrology. - November 30, 2017

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Will Pig Organs Be Used for Transplants? - (Registration required, but free.) 5-minute commentary video from Medscape Nephrology. - November 29, 2017

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Organ Transplants Involve Nationwide Exchange Program - Article from MassLive. - November 29, 2017

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Using CRISPR to Inactivate Endogenous Retroviruses in Pigs: an Important Step toward Safe Xenotransplantation? - Article in Press Abstract from Kidney International. - November 29, 2017

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Combining Machine and Nanoparticles for Better Transplant Outcomes - Article from Yale News. - November 29, 2017

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Impact of Diabetes Mellitus on the Association of Vascular Disease Before Transplantation With Long-term Transplant and Patient Outcomes After Kidney - Articles in Press Abstract from American Journal Of Kidney Diseases. - November 27, 2017

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Online Patient Resources for Deceased Donor and Live Donor Kidney Recipients: a Comparative Analysis of Readability - Free, full-text, Advance Article from Clinical Kidney Journal. - November 24, 2017

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Baby A.J. Has Successful Kidney Transplant Surgery at Emory University Hospital - Article from The Emory Wheel, Fox5Atlanta.com and International Business Times. - November 23, 2017

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Impact of Immunosuppressive Therapy on Arterial Stiffness in Kidney Transplantation: Are All Treatments the Same? - Free, Full-Text, Advance Articles from Clinical Kidney Journal. - November 23, 2017

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Human Papillomavirus and Posttransplantation Cutaneous Squamous Cell Carcinoma: a Multicenter, Prospective Cohort Study - Free, Open Access, Early View article from American Journal of Transplantation. - November 22, 2017

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Online First Abstracts from Transplantation - November 22, 2017

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BEAN: Finding Love, and a Kidney, on Tinder - Article and audio from WNYC. Film web site. - November 21, 2017

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Early View Abstracts from American Journal of Transplantation - November 21, 2017

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Podcast: Early Experience with the New Kidney Allocation System — A Perspective from UNOS - CJASN Express. - November 21, 2017

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Drug Could Cut Transplant Rejection - Press release from Queen Mary University of London. Open Access article from Immunity. - November 21, 2017

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Different Dietary Patterns and New-Onset Diabetes Mellitus After Kidney Transplantation: A Cross-Sectional Study - Article in Press abstract from Journal of Renal Nutrition. - November 21, 2017

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Results of ASERTAA, a Randomized Prospective Crossover Pharmacogenetic Study of Immediate-Release Versus Extended-Release Tacrolimus in African American Kidney Transplant Recipients - Free, full-text Article in Press from American Journal of Kidney Diseases. - November 20, 2017

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Donor and Recipient Perspectives on Anonymity in Kidney Donation From Live Donors: A Multicenter Survey Study - Article in Press Abstract from American Journal Of Kidney Diseases. - November 20, 2017

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Death with Graft Function after Kidney Transplantation: a Single Center Experience - Free, Open Access, First Online article from Clinical and Experimental Nephrology. - November 20, 2017

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Cardiovascular Disease in Kidney Transplant Recipients: Japan Academic Consortium of Kidney Transplantation (JACK) Cohort Study - First Online abstract from Clinical and Experimental Nephrology. - November 20, 2017

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KDIGO Guidelines Formalize Evaluation Process, Care Approach for Kidney Donors - Article from Nephrology News & Issues. - November 20, 2017

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Public Comment on New Measures To Be Reported on Dialysis Facility Compare - Individuals can submit comments from October 25, 2017 thru December 31, 2017 via email to dialysisdata@umich.edu. Note that these measures are only being considered for reporting on Dialysis Facility Compare (and not as additions to the Star Ratings) at this time. - October 25, 2017

Comments are requested on the following measures:

  • Percentage of Prevalent Patients Waitlisted (PPPW) - (30-page pdf)
  • Standardized Waitlist Ratio (SWR) - (31-page pdf)
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Dr. Shuvo Roy and the Implantable Artificial Kidney - 35-minute YouTube video of Dr. Roy's May 2017 presentation. The Kidney Project web site and Facebook page. - October 22, 2017

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In UK, Theresa May's Shift Towards Presumed-Consent Organ Donation Praised by Charities and Patients - Article from the Independent. - October 5, 2017

blue ball Latest transplant news from the United Network for Organ Sharing (UNOS)
blue ball Kidney Transplant news stories from Yahoo! News - Continually Updated!
 
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  ANTI-REJECTION DRUG INFORMATION

blue ball Azathioprine ("Imuran") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for azathioprine and kidney transplant Continually Updated!
Corticosteroids ("Prednisone" and many others) - Drug Info from The MedMaster™ Patient Drug Information database. National Library of Medicine PubMED search results for corticosteroids and kidney transplant Continually Updated! Search results for prednisone Continually Updated!
Cyclosporine ("Sandimmune" or "Neoral") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for cyclosporine and kidney transplant Continually Updated!
Mycophenolate ("CellCept") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for mycophenolate and kidney transplant Continually Updated!
blue ball Pycnogenol ("Zenapax®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for daclizumab and kidney transplant Continually Updated!
Sirolimus ("Rapamune®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for sirolimus and kidney transplant Continually Updated!
Tacrolimus ("Prograf" or FK506) - Drug Info from Medline Plus. National Library of Medicine PubMED search results for tacrolimus and kidney transplant Continually Updated!
 

  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Kidney Transplantation
blue ball Alliance for Paired Donation web site
Bienvenido a Infórmate - kidney transplantation information for Hispanic/Latino patients from the National Kidney Foundation
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Brochure Addresses Patients' Questions about Transplant Candidate Kidney Evaluation and Listing - PDF Resource from the United Network for Organ Sharing

Center and OPO Specific Reports from the Scientific Registry of Transplant Recipients web site
Financial Assistance for Living Donors web site
The Gift that Heals: Stories of hope, renewal and transformation through organ and tissue donation - book by Reg Green
Guidelines for Preventing Transmission of Human Immunodeficiency Virus Through Transplantation of Human Tissue and Organs from the CDC - May 20, 1994
Help Hope Live web site
How the Transplant Waiting List Works - Article from the Renal Support Network - April 2012
blue ball Hundreds of Interlaced Fingers: A Kidney Doctor's Search for the Perfect Match - A young, hopeful doctor's memoir (book) --an unforgettable love story and an informative journey into the world of medicine and kidney transplantation that ultimately asks: What does it mean to let go of something that you love, even if it is life itself?

The Jewish Kidney & Transplant Support Center - Advice and support for kidney transplant and dialysis patients

Kidney/Pancreas Transplant Program from the Johns Hopkins Medical Institutions
Kidney Transplant  web sites from Yahoo!
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Kidney Transplant eBook - by Dr. Leonardo V. Riella - September 2016

Living Kidney Donor Network
Living Kidney Donor Search
Living Kidney Donor Search Tools and Tips web site
Living Donors Online Message Board discussion page
Medical Complications of Kidney Transplantation (Hardcover) by Claudio Ponticelli (Editor) - January 2008
National Donor Memorial web site+
National Foundation for Transplants web site
National Kidney Registry web site
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National Living Donor Assistance Center - Website developed by Transplant Informatics Institute, a subsidiary of UNOS.

National Service Framework for Renal Services: Part One - Dialysis and transplantation - Department of Health web site

Organ Donation Toolbox - from the Organ Donation and Transplantation Alliance web site

Organdonor.gov video explains donation, transplantation processes

The Organ Procurement and Transplantation Network (OPTN) weekly updated Waiting Lists for transplants.
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
Organ Transplant from the University of Southern California web site
Pediatric Transplantation web site+
Pregnancy After Transplant from the Transplant Living web site
Influenza and Transplant Recipients: Ways To Prevent And Treat - Conversations in Transplantation from the American Society of Transplantation - November 2010
Q&A on Living Donation from the NKF web site
Questions About Kidney Transplantation from TransWeb.org web site
blue ball Renal Transplantation - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
The Scientific Registry of Transplant Recipients (SRTR) web site.
Top 10 Myths About Donation & Transplantation from TransWeb.org web site
Transplantation and Organ and Tissue Donors and Transplant Recipients from the NKF web site.
TransplantLiving - the patient's connection to the transplant community from UNOS
Update: Investigations of West Nile Virus Infections in Recipients of Organ Transplantation and Blood Transfusion - from MMWR - September 20, 2002
UNOS Corporate Annual Report from the United Network for Organ Sharing (UNOS)
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UNOS Transplant Pro - website for transplant professionals

Who is Eligible for Medicare? from the The Official U.S. Government Site for Medicare Information
 
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  ESSENTIALS AND CLASSICS

blue ball Transplantation Fact Sheet (pdf) from the American Nephrology Nurses’ Association
European Best Practice Guideline for Transplantation Part 1 and European Best Practice Guideline for Transplantation Part 2 - guidelines endorsed by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA)
Treatment Methods for Kidney Failure: Kidney Transplantation from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
End-Stage Renal Disease: Choosing a Treatment That's Right for You: Transplantation from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
HLA Matching from the University of Michigan Medical Center.
 
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  KDIGO™ -  Kidney Disease: Improving Global Outcomes
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Kidney Disease Improving Global Outcomes (KDIGO) web site

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  PUBMED SEARCHES

kidney transplant Continually Updated!
organ donor and kidney Continually Updated!
renal transplant and HLA matching Continually Updated!
kidney transplant and complications Continually Updated!
kidney transplant and rejection Continually Updated!
 
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  LAPAROSCOPIC NEPHRECTOMY

Live Doner Laparoscopic Nephrectomy For Kidney Transplantation - article from the University of Southern California Kidney Transplant Program.

Here is a listing of articles on the laparoscopic nephrectomy procedure from the latest scientific journals (PubMed search).

 
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  NON-DIRECTED DONATION AND "SWAPS"

 
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  STATISTICS

blue ball U.S. Facts About Kidney Transplantation from the Organ Procurement and Transplantation Network (OPTN) web site
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  UPCOMING EVENTS

blue ball Listing of North American Transplant Coordinators Organization (NATCO) Meetings
 
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  TRANSPLANT CENTERS

blue ball US Transplant Centers - from the OPTN web site
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  XENOTRANSPLANTATION, BIOTECH, AND STEM CELL RESEARCH

blue ball FDA Guidance for Industry on Xenotransplantation from the U.S. Food & Drug Administration
blue ball These two web sites provide opposing viewpoints on xenotransplantation. Here is the the International Xenotransplantation Association.
blue ball U.S. Public Health Service Guideline on Infectious Disease Issues in Xenotransplantation from the Morbidity & Mortality Weekly Report (MMWR) - August 24, 2001
blue ball Stem Cell Information - from the National Institutes of Health
blue ball Stem Cell Research - Full coverage page from Yahoo
blue ball Beyond Transplants: Growing Organs in the Lab from Popular Mechanics
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Interspecies Organogenesis-Derived Tissues for Transplantation - free, full-text articles from Transplantation - July 2017

blue ball 24-minute Video from The Kidney Project Facebook Page on their Implantable Artificial Kidney - This is a UCSF project headed by Shuvo Roy
 
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  DISCUSSION FORUM

blue ball General Nursing Discussion Forum - RenalWEB Discussion Forum
 
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  INPUT / SUGGESTIONS

blue ball E-mail to RenalWEB on the Transplantation Topic
 
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