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Last Updated 03/12/17
   

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Kidney transplants are the second most common transplant operation in the United States (over 14,000 cases per year - cornea transplants are first). Compared to heart, lung, or liver transplants, it is an easier and less complicated operation.

The United Network for Organ Sharing (UNOS) is the private organization that runs the US transplant system under a contract with the federal government.

Despite continuing advances in medicine and technology, the demand for kidneys drastically outstrips the number of donors. In October 2002, there were 53,000 persons on waiting lists for kidney transplants in the US.

There are two types of kidney transplantation: cadaveric and living donor. Cadaver organs are distributed to those on a waiting list based on criteria set forth by UNOS. L8ive donor transplantation has become increasingly common, due in large part to the success of the procedure and the shortage of cadaveric organs. Living donation allows the immediate transplantation of kidneys into recipients so operations can be scheduled electively once a suitable living donor has been identified. This avoids the long waiting times encountered with cadaveric donation. A new procedure, the laparoscopic nephrectomy, has greatly reduced the trauma and recovery period for a living donor.

Kidney transplant recipients usually must take immunosuppressants, or anti-rejection drugs, for the rest of their lives. Medicare coverage for these medications is currently limited to three years, but federal legislation has been introduced to extend coverage. Immunosuppressant medications run on average between $1,000 - $1,200 monthly.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Automated Reminders and Physician Notification to Promote Immunosuppression Adherence Among Kidney Transplant Recipients: A Randomized Trial - Free, Full-Text Article from American Journal Of Kidney Diseases. - March 2017

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Emotional Bonding in Recipients of Deceased Donor Kidney Transplants (DDRT): Associated Factors - National Kidney Foundation 2017 Spring Clinical Meetings Abstract from Advances in Chronic Kidney Disease. - March 2017

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Should Belatacept Be The Centrepiece of Renal Transplantation? - (Registration required, but free.) Free full-text article from NDT via Medscape Nephrology. - March 10, 2017

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Living Kidney Transplant Donation: Myths vs. Facts - Press release from New York-Presbyterian Hospital. - March 9, 2017

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Researchers Identify a New Way to Promote Tissue Regeneration - Press release from Houston Methodist. - March 9, 2017

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FDA Warns of Contaminated Organ Preservation Solution - March 9, 2017

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Longitudinal Assessment of Myocardial Function in Childhood Chronic Kidney Disease, during Dialysis, and Following Kidney Transplantation - First Online abstract from Pediatric Nephrology. - March 8, 2017

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For Organ Transplant Recipients, Skin Diseases and Risk Factors Differ by Race - Press release from Drexel University. - March 8, 2017

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Common Cold Can Be Surprisingly Dangerous for Transplant Patients - Press release from Fred Hutchinson Cancer Research Center. - March 7, 2017

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Understanding Trends in Kidney Function 1 Year after Kidney Transplant in the United States - JASN Express Abstract. - March 7, 2017

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New Method Rescues Donor Organs to Save Lives - Press release and video from Columbia University School of Engineering and Applied Science. - March 6, 2017

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Association of Clinical Events With Everolimus Exposure in Kidney Transplant Patients Receiving Low Doses of Tacrolimus - Free, Open Access, Early View article from American Journal of Transplantation. - March 4, 2017

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Living Donor Protection Act Reintroduced in House - Article from Nephrology News & Issues. - March 3, 2017

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Transplant as a Competing Risk in the Analysis of Dialysis Patients - Advance Access abstract from NDT. - March 3, 2017

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Researchers Can Put Organs in a Deep Freeze. Scientists Say They May Have a Way to Bring Them Back - Article from STAT. - March 1, 2017

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A Case-Based Analysis of Whether Living Related Donors Listed for Transplant Share ESRD Causes with Their Recipients - CJASN Express abstract. - March 1, 2017

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Chlorthalidone Versus Amlodipine for Hypertension in Kidney Transplant Recipients Treated With Tacrolimus: A Randomized Crossover Trial - Articles in Press Abstract from American Journal of Kidney Diseases. - March 1, 2017

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Advance Access Abstracts from NDT - February 27, 2017

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Timing of Anti-Donor Antibody Responses Affects the Survival of Kidney Transplants - Press release and JASN Express abstract from the American Society of Nephrology. - February 24, 2017

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Metrics and Data Analysis in Transplantation: Quality Improvement via Transparency - Free, full-text, Early View editorial from American Journal of Transplantation. - February 24, 2017

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Evaluation of Renal Function in a Specific Population of Living Kidney Donors - Early View abstract from Journal of Renal Care. - February 24, 2017

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HIV+ Kidney Failure Patients Face Hurdles in Receiving Necessary Transplants - Press release and CJASN Express abstract from the American Society of Nephrology. - February 23, 2017

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Transplant Infectious Diseases: A Review of the Scientific Registry of Transplant Recipients Published Data - Early View abstract from American Journal of Transplantation. - February 23, 2017

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New York State Considers Bill to Pay Live Organ Donors' Costs - Article from Crain's New York Business. - February 23, 2017

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Organ Transplant Programs Are so Prestigious, They're Sparking Crosstown Rivalry in Chicago - (Registration required, but free.) Article from Modern Healthcare. - February 22, 2017

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Compensating Kidney Donors Is Supported by Over 85% of US Adults as Reported by Acumen Health Research Institute - February 20, 2017

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Infectious Complications As the Leading Cause of Death after Kidney Transplantation: Analysis of More Than 10,000 Transplants from a Single Center (in Brazil) - First Online abstract from Journal of Nephrology. - February 17, 2017

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Risk Prediction Models for Graft Failure in Kidney Transplantation: a Systematic Review - Advance Articles Abstract from NDT. - February 16, 2017

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Discovery May Help Prevent Tissue Scarring and Rejection of Transplanted Kidneys - February 16, 2017

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Early Conversion From Calcineurin Inhibitor- to Everolimus-Based Therapy Following Kidney Transplantation: Results of the Randomized ELEVATE Trial - Early View abstract from American Journal of Transplantation. - February 14, 2017

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Pregnancy in Chronic Kidney Disease and Kidney Transplantation - Article in Press abstract from Kidney International. - February 13, 2017

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Seasonal Variations in Transition, Mortality and Kidney Transplantation among Patients with End-Stage Renal Disease in the USA - Advance Access Abstract from NDT. - February 11, 2017

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Long-term Risks of Kidney Living Donation: Review and Position Paper by The ERA-EDTA DESCARTES Working Group - Abstract from NDT. - February 10, 2017

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Free, Full-Text Articles from American Journal of Transplantation - January 27, 2017

blue ball Latest transplant news from the United Network for Organ Sharing (UNOS)
blue ball Kidney Transplant news stories from Yahoo! News - Continually Updated!
 
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  ANTI-REJECTION DRUG INFORMATION

blue ball Azathioprine ("Imuran") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for azathioprine and kidney transplant Continually Updated!
Corticosteroids ("Prednisone" and many others) - Drug Info from The MedMaster™ Patient Drug Information database. National Library of Medicine PubMED search results for corticosteroids and kidney transplant Continually Updated! Search results for prednisone Continually Updated!
Cyclosporine ("Sandimmune" or "Neoral") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for cyclosporine and kidney transplant Continually Updated!
Mycophenolate ("CellCept") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for mycophenolate and kidney transplant Continually Updated!
blue ball Pycnogenol ("Zenapax®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for daclizumab and kidney transplant Continually Updated!
Sirolimus ("Rapamune®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for sirolimus and kidney transplant Continually Updated!
Tacrolimus ("Prograf" or FK506) - Drug Info from Medline Plus. National Library of Medicine PubMED search results for tacrolimus and kidney transplant Continually Updated!
 

  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Kidney Transplantation
blue ball Alliance for Paired Donation web site
Bienvenido a Infórmate - kidney transplantation information for Hispanic/Latino patients from the National Kidney Foundation
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Brochure Addresses Patients' Questions about Transplant Candidate Kidney Evaluation and Listing - PDF Resource from the United Network for Organ Sharing

Center and OPO Specific Reports from the Scientific Registry of Transplant Recipients web site
Financial Assistance for Living Donors web site
The Gift that Heals: Stories of hope, renewal and transformation through organ and tissue donation - book by Reg Green
Guidelines for Preventing Transmission of Human Immunodeficiency Virus Through Transplantation of Human Tissue and Organs from the CDC - May 20, 1994
Help Hope Live web site
How the Transplant Waiting List Works - Article from the Renal Support Network - April 2011

The Jewish Kidney & Transplant Support Center - Advice and support for kidney transplant and dialysis patients

Kidney/Pancreas Transplant Program from the Johns Hopkins Medical Institutions
Kidney Transplant  web sites from Yahoo!
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Kidney Transplant eBook - by Dr. Leonardo V. Riella - September 2016

Living Kidney Donor Network
Living Kidney Donor Search
Living Kidney Donor Search Tools and Tips web site
Living Donors Online Message Board discussion page
Medical Complications of Kidney Transplantation (Hardcover) by Claudio Ponticelli (Editor) - January 2008
National Donor Memorial web site
National Foundation for Transplants web site
National Kidney Registry web site
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National Living Donor Assistance Center - Website developed by Transplant Informatics Institute, a subsidiary of UNOS.

National Service Framework for Renal Services: Part One - Dialysis and transplantation - Department of Health web site

Organ Donation Toolbox - from the Organ Donation and Transplantation Alliance web site

Organdonor.gov video explains donation, transplantation processes

The Organ Procurement and Transplantation Network (OPTN) weekly updated Waiting Lists for transplants.
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
Organ Transplant from the University of Southern California web site
Pediatric Transplantation web site
Pregnancy After Transplant from the Transplant Living web site
Influenza and Transplant Recipients: Ways To Prevent And Treat - Conversations in Transplantation from the American Society of Transplantation - November 2010
Q&A on Living Donation from the NKF web site
Questions About Kidney Transplantation from TransWeb.org web site
blue ball Renal Transplantation - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
The Scientific Registry of Transplant Recipients (SRTR) web site.
Top 10 Myths About Donation & Transplantation from TransWeb.org web site
Transplantation and Organ and Tissue Donors and Transplant Recipients from the NKF web site.
TransplantLiving - the patient's connection to the transplant community from UNOS
Update: Investigations of West Nile Virus Infections in Recipients of Organ Transplantation and Blood Transfusion - from MMWR - September 20, 2002
UNOS Corporate Annual Report from the United Network for Organ Sharing (UNOS)
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UNOS Transplant Pro - website for transplant professionals

Who is Eligible for Medicare? from the The Official U.S. Government Site for Medicare Information
 
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  ESSENTIALS AND CLASSICS

blue ball Transplantation Fact Sheet (pdf) from the American Nephrology Nurses’ Association
European Best Practice Guideline for Transplantation Part 1 and European Best Practice Guideline for Transplantation Part 2 - guidelines endorsed by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA)
Treatment Methods for Kidney Failure: Kidney Transplantation from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
End-Stage Renal Disease: Choosing a Treatment That's Right for You: Transplantation from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
HLA Matching from the University of Michigan Medical Center.
 
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  KDIGO™ -  Kidney Disease: Improving Global Outcomes
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Kidney Disease Improving Global Outcomes (KDIGO) web site

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  PUBMED SEARCHES

kidney transplant Continually Updated!
organ donor and kidney Continually Updated!
renal transplant and HLA matching Continually Updated!
kidney transplant and complications Continually Updated!
kidney transplant and rejection Continually Updated!
 
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  LAPAROSCOPIC NEPHRECTOMY

Live Doner Laparoscopic Nephrectomy For Kidney Transplantation - article from the University of Southern California Kidney Transplant Program.

Here is a listing of articles on the laparoscopic nephrectomy procedure from the latest scientific journals (PubMed search).

 
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  NON-DIRECTED DONATION AND "SWAPS"

 
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  STATISTICS

blue ball U.S. Facts About Kidney Transplantation from the Organ Procurement and Transplantation Network (OPTN) web site
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  UPCOMING EVENTS

blue ball Listing of North American Transplant Coordinators Organization (NATCO) Meetings
 
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  TRANSPLANT CENTERS

blue ball US Transplant Centers - from the OPTN web site
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  XENOTRANSPLANTATION, BIOTECH, AND STEM CELL RESEARCH

blue ball FDA Guidance for Industry on Xenotransplantation from the U.S. Food & Drug Administration
blue ball These two web sites provide opposing viewpoints on xenotransplantation. Here is the the International Xenotransplantation Association. Here is the web site of the Campaign for Responsible Transplantation, a group that opposes xenotransplantation.
blue ball U.S. Public Health Service Guideline on Infectious Disease Issues in Xenotransplantation from the Morbidity & Mortality Weekly Report (MMWR) - August 24, 2001
blue ball Stem Cell Information - from the National Institutes of Health
blue ball Stem Cell Research - Full coverage page from Yahoo
blue ball Beyond Transplants: Growing Organs in the Lab from Popular Mechanics
blue ball 24-minute Video from The Kidney Project Facebook Page on their Implantable Artificial Kidney - This is a UCSF project headed by Shuvo Roy
 
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  DISCUSSION FORUM

blue ball General Nursing Discussion Forum - RenalWEB Discussion Forum
 
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  INPUT / SUGGESTIONS

blue ball E-mail to RenalWEB on the Transplantation Topic
 
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