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Last Updated 10/22/17
   

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Kidney transplants are the second most common transplant operation in the United States (over 16,500 cases per year - cornea transplants are first). Compared to heart, lung, or liver transplants, it is an easier and less complicated operation.

The United Network for Organ Sharing (UNOS) is the private organization that runs the US transplant system under a contract with the federal government.

Despite continuing advances in medicine and technology, the demand for kidneys drastically outstrips the number of donors. In 2013, there were over 96,000 persons on waiting lists for kidney transplants in the US.

There are two types of kidney transplantation: cadaveric and living donor. Cadaver organs are distributed to those on a waiting list based on criteria set forth by UNOS. Live donor transplantation has become increasingly common, due in large part to the success of the procedure and the shortage of cadaveric organs. Living donation allows the immediate transplantation of kidneys into recipients so operations can be scheduled electively once a suitable living donor has been identified. This avoids the long waiting times encountered with cadaveric donation. A new procedure, the laparoscopic nephrectomy, has greatly reduced the trauma and recovery period for a living donor.

Kidney transplant recipients usually must take immunosuppressants, or anti-rejection drugs, for the rest of their lives. Medicare coverage for these medications is currently limited to three years, but federal legislation has been introduced to extend coverage. Immunosuppressant medications run on average between $1,000 - $1,200 monthly.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Near the Campus Cow Pasture, a Scientist Works to Grow Human Organs—in Pigs - Article from STAT. - October 20, 2017

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Center Variation and the Effect of Center and Provider Characteristics on Clinical Outcomes in Kidney Transplantation: A Systematic Review of the Evidence - Free, full-text article from Canadian Journal of Kidney Health and Disease. - October 19, 2017

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Direct Acting Antiviral Agent-based Regimen for HCV Recurrence after Combined Liver-Kidney Transplantation: Results from the ANRS CO23 CUPILT Study - Early View abstract from American Journal of Transplantation. - October 19, 2017

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In UK, Hundreds of Families Block Organ Donation - Article from the BBC. - October 19, 2017

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Re-Establishing Brain Networks in Patients with ESRD after Successful Kidney Transplantation - CJASN Express abstract. - October 18, 2017

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Free, Full-Text, Advance Articles from Clinical Kidney Journal - October 18, 2017

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A Kidney Offer Acceptance Decision Tool to Inform the Decision to Accept an Offer or Wait for a Better Kidney - Early View abstract from American Journal of Transplantation. - October 17, 2017

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New-Onset Diabetes after Kidney Transplantation: Can the Risk Be Modified by Choosing Immunosuppression Regimen Based on Pretransplant Viral Serology? - Advance Article Abstract from NDT. - October 16, 2017

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Normothermic ex vivo Kidney Perfusion for Graft Quality Assessment Prior to Transplantation - Early View abstract from American Journal of Transplantation. - October 16, 2017

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Transplant Tourism Following the Declaration of Istanbul: Poor Outcomes and Nephrologist Dilemma - Accepted Article abstract from Nephrology. - October 14, 2017

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A Markov Analysis of Screening for Late-Onset Cytomegalovirus Disease in Cytomegalovirus High-Risk Kidney Transplant Recipients - CJASN Express Abstract. - October 12, 2017

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No Significant Differences in Short-Term Renal Prognosis between Living Kidney Donors with and without Diabetes - Free, Open Access, First Online article from Clinical and Experimental Nephrology. - October 12, 2017

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Venous Thromboembolism and the Risk of Death and Graft Loss in Kidney Transplant Recipients - Issue in Press abstract from American Journal of Nephrology. - October 12, 2017

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Difficult Conversations: Australian Indigenous Patients' Views on Kidney Transplantation - Free, Open Access article from BMC Nephrology. - October 11, 2017

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Overcoming Pre-Existing Alloantibody in Renal Transplantation — Improving Outcomes While Reducing Needs and Costs - Free, full-text, Early View editorial from American Journal of Transplantation. - October 10, 2017

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New Report Offers Framework for Research on Organ Transplantation - Press release and publication from the National Academies of Sciences, Engineering, and Medicine. Free, full-text, New Online viewpoint article from the Journal of the American Medical Association. - October 10, 2017

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Precision Transplant Medicine: Biomarkers to the Rescue - JASN Express Abstract. - October 9, 2017

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The Lived Experience of “Being Evaluated” for Organ Donation — Focus Groups with Living Kidney Donors - CJASN Express abstract. - October 9, 2017

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12 Arrests in Egypt for Sale of Organs - October 9, 2017

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A Helpful Approach to Organ Donation: from End-Of-Life Care to Effective Organ Transplantation - Free, full-text, Early View letter to the editor from American Journal of Transplantation. - October 5, 2017

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'Increased Risk' Donor Organs a Tough Sell to Transplant Patients - Press release from University of Michigan. - October 5, 2017

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UK Prime Minister Theresa May Announces an Opt-Out Organ Donation System - News release from Kidney Research UK. Article from ITV. - October 4, 2017

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Lancet Commission: Stem Cells and Regenerative Medicine - Free, full-text, Online First article from The Lancet. - October 4, 2017

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Taking the Challenge: a Protocolized Approach to Optimize Pneumocystis Pneumonia Prophylaxis in Renal Transplant Recipients - Abstract of Early View Brief Communication from American Journal of Transplantation. - October 3, 2017

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Long-term Patient and Graft Survival of Kidney Transplant Recipients with Hepatitis C Virus Infection in the United States - Online First abstract from Transplantation. - October 3, 2017

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Are These Common Organ Donor Myths Stopping You From Saving a Life? — 10 Things You May Not Know About Organ Donation - Press release from New York-Presbyterian Hospital. - October 2, 2017

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Wake Forest Baptist Receives Federal Funding to Conduct National Study on Risks Associated With Kidney Transplantation - Press release from Wake Forest Baptist Medical Center. - October 2, 2017

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US States Are Waging a Civil War over Donated Livers. Will a New Proposal Finally Resolve It? - Article from STAT. - October 2, 2017

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Should All Dialysis Patients with Hepatitis C Be Treated? If so, before or after Kidney Transplantation? - Free, Full-Text Editorial from Seminars In Dialysis. - September/October 2017

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Study Offers Insights on How to Decrease the Discard Rate of Donated Organs - Press release and JASN Express abstract from the American Society of Nephrology. Article from HealthDay. - September 29, 2017

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Analysis of OPTN/UNOS Registry Suggests the Number of HLA Matches and Not Mismatches Is a Stronger Independent Predictor of Kidney Transplant Survival - Article in Press abstract from Kidney International. - September 29, 2017

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Progress Made on Robot-assisted Kidney Transplantation - (Registration required, but free.) Reuters article via Medscape Nephrology. - September 29, 2017

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Free, Full-Text Articles from American Journal of Transplantation - September 28, 2017

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Serum Phosphorus Levels and Fracture Following Renal Transplantation - article from Clinical Endocrinology - Article from Medscape Nephrology (registration required, but free). - September 27, 2017

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Rafael Matesanz: The Threat of Transplant Tourism - Opinion piece from the Latin American Herald Tribune. - September 26, 2017

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Nation’s Organ Donation Network Wants To Make Liver Transplants ‘A Little Bit More Equal’ - September 26, 2017

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Organ Donation in Ontario Increased 57 Percent Since 2006 after New Canadian Donation Policy - Press release and full-text article from Canadian Medical Association Journal. - September 25, 2017

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Strengths and Weaknesses of Using SRTR Data to Shape the Management of the HIV-Infected Kidney Transplant Recipient - Free, full-text, Early View editorial from American Journal of Transplantation. - September 23, 2017

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Scientists Grow Bullish on Pig-to-Human Transplants - Article from Science magazine. - September 22, 2017

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Kidney Allocation Based on Proven Acceptable Antigens Results in Superior Graft Survival in Highly Sensitized Patients - Article in Press abstract from Kidney International. - September 22, 2017

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How First ‘Vouchers’ in UCLA Kidney Donation Program Led to 25 Lifesaving Transplants - Press release. - September 19, 2017

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Improving Kidney Transplant Outcomes - Press release from University of Manitoba. - September 18, 2017

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First UK Case Report of Kidney Transplantation from an HIV-Infected Deceased Donor to Two HIV-Infected Recipients - Free, full-text, Advance Article from Clinical Kidney Journal. - September 18, 2017

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Harms of Unsuccessful Donation after Circulatory Death: an Exploratory Study - Early View abstract from American Journal of Transplantation. - September 18, 2017

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Selena Gomez's Kidney Transplant Puts Lupus Center Stage - Article from HealthDay. - September 15, 2017

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This Gift Voucher Might Just Get You A Kidney - Article from Kaiser Health News. - September 15, 2017

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The Kidney Allocation System Claims Equity: It Is Time to Review Utility and Fairness - Free, full-text, Early View editorial from American Journal of Transplantation. - September 15, 2017

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The Association of Donor and Recipient Age with Graft Survival in Pediatric Renal Transplant Recipients in a European Society for Pediatric Nephrology/European Renal Association-European Dialysis and Transplantation Association Registry Study - Advance Article abstract from NDT. - September 15, 2017

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Early View Abstracts from American Journal of Transplantation - September 15, 2017

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How Spain Became the World Leader in Organ Transplants - Article from THE LOCAL. - September 15, 2017

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National Kidney Foundation Statement on Selena Gomez and Living Organ Donation - NKF news release. - September 14, 2017

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Skin Cancers in Organ Transplant Recipients - Early View abstract from American Journal of Transplantation. - September 14, 2017

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University of Rhode Island Research Examines Cause of Kidney Transplant Failures - Press release. - September 14, 2017

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Start-up Working on Breakthrough in 3-D Printing of Human Organs - Article from Healthcare IT News. - September 14, 2017

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New Material With Live Cells for Organ, Tissue Printing - Article from MedGadget. - September 14, 2017

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Transplanting HCV-Infected Kidneys into Uninfected Recipients - Free, full-text correspondence from the New England Journal of Medicine. - September 14, 2017

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Management Considerations in the Failing Renal Allograft - Accepted Article abstract and full-text 25-page PDF from Nephrology. - September 14, 2017

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Selena Gomez Receives Kidney Transplant From Best Friend - September 14, 2017

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Implantable Artificial Kidney Developers Working with Patients on Device Development - Article from Nephrology News & Issues. - September 13, 2017

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Free, Full-Text, Early View Letters to the Editor from American Journal of Transplantation - September 13, 2017

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Effect of Renal Transplantation on Cognitive Function in Hemodialysis Patients: a Longitudinal Study - First Online abstract from International Urology and Nephrology. - September 12, 2017

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Early View Abstracts from American Journal of Transplantation - September 12, 2017

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Articles from Medscape Nephrology (registration required, but free) - September 12, 2017

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Pediatric Renal Transplantation: Moving Forward in the Field - Free, full-text editorial from Pediatric Nephrology. - July 28, 2017

blue ball Latest transplant news from the United Network for Organ Sharing (UNOS)
blue ball Kidney Transplant news stories from Yahoo! News - Continually Updated!
 
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  ANTI-REJECTION DRUG INFORMATION

blue ball Azathioprine ("Imuran") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for azathioprine and kidney transplant Continually Updated!
Corticosteroids ("Prednisone" and many others) - Drug Info from The MedMaster™ Patient Drug Information database. National Library of Medicine PubMED search results for corticosteroids and kidney transplant Continually Updated! Search results for prednisone Continually Updated!
Cyclosporine ("Sandimmune" or "Neoral") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for cyclosporine and kidney transplant Continually Updated!
Mycophenolate ("CellCept") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for mycophenolate and kidney transplant Continually Updated!
blue ball Pycnogenol ("Zenapax®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for daclizumab and kidney transplant Continually Updated!
Sirolimus ("Rapamune®") - Drug Info from Medline Plus. National Library of Medicine PubMED search results for sirolimus and kidney transplant Continually Updated!
Tacrolimus ("Prograf" or FK506) - Drug Info from Medline Plus. National Library of Medicine PubMED search results for tacrolimus and kidney transplant Continually Updated!
 

  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Kidney Transplantation
blue ball Alliance for Paired Donation web site
Bienvenido a Infórmate - kidney transplantation information for Hispanic/Latino patients from the National Kidney Foundation
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Brochure Addresses Patients' Questions about Transplant Candidate Kidney Evaluation and Listing - PDF Resource from the United Network for Organ Sharing

Center and OPO Specific Reports from the Scientific Registry of Transplant Recipients web site
Financial Assistance for Living Donors web site
The Gift that Heals: Stories of hope, renewal and transformation through organ and tissue donation - book by Reg Green
Guidelines for Preventing Transmission of Human Immunodeficiency Virus Through Transplantation of Human Tissue and Organs from the CDC - May 20, 1994
Help Hope Live web site
How the Transplant Waiting List Works - Article from the Renal Support Network - April 2012
blue ball Hundreds of Interlaced Fingers: A Kidney Doctor's Search for the Perfect Match - A young, hopeful doctor's memoir (book) --an unforgettable love story and an informative journey into the world of medicine and kidney transplantation that ultimately asks: What does it mean to let go of something that you love, even if it is life itself?

The Jewish Kidney & Transplant Support Center - Advice and support for kidney transplant and dialysis patients

Kidney/Pancreas Transplant Program from the Johns Hopkins Medical Institutions
Kidney Transplant  web sites from Yahoo!
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Kidney Transplant eBook - by Dr. Leonardo V. Riella - September 2016

Living Kidney Donor Network
Living Kidney Donor Search
Living Kidney Donor Search Tools and Tips web site
Living Donors Online Message Board discussion page
Medical Complications of Kidney Transplantation (Hardcover) by Claudio Ponticelli (Editor) - January 2008
National Donor Memorial web site
National Foundation for Transplants web site
National Kidney Registry web site
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National Living Donor Assistance Center - Website developed by Transplant Informatics Institute, a subsidiary of UNOS.

National Service Framework for Renal Services: Part One - Dialysis and transplantation - Department of Health web site

Organ Donation Toolbox - from the Organ Donation and Transplantation Alliance web site

Organdonor.gov video explains donation, transplantation processes

The Organ Procurement and Transplantation Network (OPTN) weekly updated Waiting Lists for transplants.
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
Organ Transplant from the University of Southern California web site
Pediatric Transplantation web site
Pregnancy After Transplant from the Transplant Living web site
Influenza and Transplant Recipients: Ways To Prevent And Treat - Conversations in Transplantation from the American Society of Transplantation - November 2010
Q&A on Living Donation from the NKF web site
Questions About Kidney Transplantation from TransWeb.org web site
blue ball Renal Transplantation - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
The Scientific Registry of Transplant Recipients (SRTR) web site.
Top 10 Myths About Donation & Transplantation from TransWeb.org web site
Transplantation and Organ and Tissue Donors and Transplant Recipients from the NKF web site.
TransplantLiving - the patient's connection to the transplant community from UNOS
Update: Investigations of West Nile Virus Infections in Recipients of Organ Transplantation and Blood Transfusion - from MMWR - September 20, 2002
UNOS Corporate Annual Report from the United Network for Organ Sharing (UNOS)
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UNOS Transplant Pro - website for transplant professionals

Who is Eligible for Medicare? from the The Official U.S. Government Site for Medicare Information
 
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  ESSENTIALS AND CLASSICS

blue ball Transplantation Fact Sheet (pdf) from the American Nephrology Nurses’ Association
European Best Practice Guideline for Transplantation Part 1 and European Best Practice Guideline for Transplantation Part 2 - guidelines endorsed by the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA)
Treatment Methods for Kidney Failure: Kidney Transplantation from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK)
End-Stage Renal Disease: Choosing a Treatment That's Right for You: Transplantation from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
HLA Matching from the University of Michigan Medical Center.
 
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  KDIGO™ -  Kidney Disease: Improving Global Outcomes
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Kidney Disease Improving Global Outcomes (KDIGO) web site

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  PUBMED SEARCHES

kidney transplant Continually Updated!
organ donor and kidney Continually Updated!
renal transplant and HLA matching Continually Updated!
kidney transplant and complications Continually Updated!
kidney transplant and rejection Continually Updated!
 
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  LAPAROSCOPIC NEPHRECTOMY

Live Doner Laparoscopic Nephrectomy For Kidney Transplantation - article from the University of Southern California Kidney Transplant Program.

Here is a listing of articles on the laparoscopic nephrectomy procedure from the latest scientific journals (PubMed search).

 
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  NON-DIRECTED DONATION AND "SWAPS"

 
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  STATISTICS

blue ball U.S. Facts About Kidney Transplantation from the Organ Procurement and Transplantation Network (OPTN) web site
blue ball OPTN / SRTR 2013 Annual Report: Transplant Data - Annual report from the U.S. Organ Procurement and Transplantation Network and the Scientific Registry of Transplant Recipients.
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  UPCOMING EVENTS

blue ball Listing of North American Transplant Coordinators Organization (NATCO) Meetings
 
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  TRANSPLANT CENTERS

blue ball US Transplant Centers - from the OPTN web site
blue ball Transplant Statistics: Center-Specific Reports from the Scientific Registry of Transplant Recipients (SRTR) web site
 
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  XENOTRANSPLANTATION, BIOTECH, AND STEM CELL RESEARCH

blue ball FDA Guidance for Industry on Xenotransplantation from the U.S. Food & Drug Administration
blue ball These two web sites provide opposing viewpoints on xenotransplantation. Here is the the International Xenotransplantation Association.
blue ball U.S. Public Health Service Guideline on Infectious Disease Issues in Xenotransplantation from the Morbidity & Mortality Weekly Report (MMWR) - August 24, 2001
blue ball Stem Cell Information - from the National Institutes of Health
blue ball Stem Cell Research - Full coverage page from Yahoo
blue ball Beyond Transplants: Growing Organs in the Lab from Popular Mechanics
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Interspecies Organogenesis-Derived Tissues for Transplantation - free, full-text articles from Transplantation - July 2017

blue ball 24-minute Video from The Kidney Project Facebook Page on their Implantable Artificial Kidney - This is a UCSF project headed by Shuvo Roy
 
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  DISCUSSION FORUM

blue ball General Nursing Discussion Forum - RenalWEB Discussion Forum
 
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  INPUT / SUGGESTIONS

blue ball E-mail to RenalWEB on the Transplantation Topic
 
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