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The leading cause of death for end-stage renal disease patients
is cardiovascular disease (CVD). Approximately 16,000 dialysis
patients die each year (1996) from CVD according to the United States
Renal Data System (USRDS).
This risk for CVD is about 30 times the risk in the general
population. Even after statistical adjustments to account
for age, CVD-related deaths remain 10 to 20 times higher than in
the general population.
The high risk of CVD in end-stage renal disease is partly due
to the fact that the dialysis patient population has a higher prevalence
of conditions that are known risk factors for CVD in the general
population, such as older age, hypertension (high blood pressure),
high cholesterol levels, diabetes, and physical inactivity. The
high risk may also be partly caused by factors involved in renal
failure, including proteinuria (protein in urine), fluid retention,
irregular blood chemistries, anemia, blood clotting disorders, and
chronic inflammation.
The two most common CVD conditions seen in patients with end-stage
renal disease are coronary artery disease (CAD) and left ventricular
hypertrophy (LVH). The physical symptoms of these two conditions
may often be the same, and include chest pain, heart attack, congestive
heart failure, and arrhythmias.
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Factors
Predicting Mortality in Elderly Patients on Dialysis - Issue-in-Progress
abstract from Nephron Clinical Practice. - February 19, 2010 |
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Median
Intradialytic Blood Pressure Can Track Changes Evoked by Probing Dry-Weight
- CJASN Express abstract. - February 18, 2010 |
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Happiness
Makes for a Healthy Heart - Article from Reuters. - February 18, 2010 |
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Kidney
and Brain—a Renal Perspective of ‘Les Liaisons Dangereuses’
- Free, full-text, Advance Access editorial commentary from NDT. - February
17, 2010 |
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Many
Patients May Never Fill New Prescriptions for Diabetes and Hypertension
- Article from Reuters. - February 17, 2010 |
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Diabetes
Risk of Statins Outweighed by Heart Benefit - Article from Medpage Today.
- February 17, 2010 |
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High
Levels of Vitamin D in Older People Can Reduce Heart Disease and Diabetes
- Article from Warwick Medical School. - February 15, 2010 |
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Low
Levels of Natural Antibodies Behind Stroke - Article from the Karolinska
Institutet. - February 12, 2010 |
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Study
Finds New Stent Improves Ability To Keep Vessels Open for Dialysis Patients
- Press release from the University of Maryland Medical Center and abstract
from The New England Journal of Medicine (NEJM) . Extract
of NEJM editorial. - February 10, 2010 |
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Circulating
Monocyte Subpopulations with High Expression of Angiotensin-Converting Enzyme
Predict Mortality in ESRD Patients - Advance Access abstract from NDT.
- February 10, 2010 |
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Cardiac
Science Automated External Defibrillators (Powerheart, Cardiovive, CardioLife
models): Recall - Safety information from FDA. - February 9, 2010 |
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FDA
Okays Statin for Primary Prevention of Cardiovascular Disease - Article
from MedPage Today. - February 8, 2010 |
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Research
Warns of Risks of Low Potassium in Heart Failure Patients with CKD -
Press release from the University of Alabama at Birmingham. - February 8,
2010 |
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Using
Vertebral Bone Densitometry To Determine Aortic Calcification in Patients
with Chronic Kidney Disease - Abstract of accepted article from Nephrology.
- February 5, 2010 |
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Cardiovascular
Effects of Angiotensin Converting Enzyme Inhibition or Angiotensin Receptor
Blockade in Hemodialysis: A Meta-Analysis - CJASN Express abstract.
- February 4, 2010 |
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Higher
Systolic Blood Pressure Is Associated with Progression of Carotid Intima–Media
Thickness in Patients with CKD - Advance online abstract from Kidney
International. - February 3, 2010 |
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As
Use of Herbal Remedies Soars, Patients Taking These and Cardiovascular Medications
May be at Heightened Risk of Dangerous, Potentially Life-Threatening Interactions
- Article from the Mayo Clinic. - February 1, 2010 |
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Blood
Pressure in CKD Stage 5D—Report from a Kidney Disease: Improving Global
Outcomes Controversies Conference - Free, full-text, meeting report
from Kidney International. - February 1, 2010 |
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Pediatrics:
Blood Pressure Target for Renoprotection in Children - Free, full-text
article from Nature Reviews Nephrology. - February 2010 |
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Statin
Prescription is Essential in Peripheral Vascular Disease - Free, full-text
CME article from the Journal of Vascular and Interventional Radiology. -
February 2010 |
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Echocardiography
in Chronic Kidney Disease: Diagnostic and Prognostic Implications -
Free, full-text, Issue-in-Progress minireview from Nephron Clinical Practice.
- February 2010 |
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AURORA:
Is There a Role for Statin Therapy in Dialysis Patients? - Free, full-text
article from AJKD. - February 2010 |
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Effects
of Dialysis Purity on Uremic Dyslipidemia - Free, full-text article
from Therapeutic Apheresis and Dialysis. - January 2010 |
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Guidelines
Needed To Improve Care for Patients with MI, Chronic Kidney Disease
- Report from Cardiology Today. - January 28, 2010 |
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Study
Design and Subject Baseline Characteristics in the ADVANCE Study: Effects
of Cinacalcet on Vascular Calcification in Hemodialysis Patients - Advance
Access abstract from NDT. - January 27, 2010 |
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Magnesium
in Chronic Kidney Disease: Challenges and Opportunities - (13-page pdf)
Free, full-text, minireview from Blood Purification. - January 26, 2010 |
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Perioperative
Outcomes Among ESRD Patients Following Coronary Artery Bypass Surgery in
US - Advance Access abstract from NDT. - January 26, 2010 |
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More
High Blood Pressure Worries: It's Linked to Dementia - Article from
AP. - January 26, 2010 |
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Soluble
Fas: a useful marker of inflammation and cardiovascular diseases in uremic
patients - Abstract from Clinical and Experimental Nephrology. - January
25, 2010 |
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Low-carb
Diet Effective at Lowering Blood Pressure - Release from Duke University
Medical Center. - January 25, 2010 |
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Albuminuria
and Heart Disease Linked Only in White Diabetics - Article from Renal
and Urology News. - January 22, 2010 |
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Home-based
vs. Center-based Cardiac Rehabilitation: Cochrane Systematic Review and
Meta-Analysis - Free, full-text article from British Medical Journal.
- January 19, 2010 |
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Lower
Afib Risk Seen with Some Antihypertensives More than Others - Article
from Medpage Today. - January 19, 2010 |
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Blood
Pressure and Mortality Among Hemodialysis Patients - Abstract from Hypertension.
- January 18, 2010 |
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Sodium
Thiosulfate Delays the Progression of Coronary Artery Calcification in Hemodialysis
Patients - Advance Access abstract from NDT. - January 18, 2010 |
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The
Role of Vitamin D Receptors and Activators in Cardiovascular and Kidney
Health - 8-page pdf from KDIGO. - January 15, 2010 |
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Increased
Left Ventricular Mass in Chronic Kidney Disease and End-Stage Renal Disease:
What Are the Implications? - Full-text article from Dialysis & Transplantation.
- January 14, 2010 |
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Myocardial
Fibrosis and Diastolic Dysfunction in Patients on Chronic Hemodialysis
- Advance Access abstract from NDT. - January 14, 2010 |
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News
Releases from the American Heart Association Continually
Updated! |
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Newsworthy
Events and New Features - from the American Heart Association Continually
Updated! |
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Latest
Cardiovascular Disease News Stories - Yahoo! News Continually
Updated! |
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Latest
Hypertension News Stories - Yahoo! News Continually Updated! |
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