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| The leading cause of death for end-stage renal disease patients
is cardiovascular disease (CVD). In the prevalent dialysis
population, the percentage of deaths due to cardiac disease has
fallen from 45 in 1997–1999 to 39 in 2007–2009; the
percentage attributable to cardiovascular disease has declined from
50 to 42 according to the United States Renal Data System (USRDS).
This risk for CVD is about 30 times the risk in the general
population. Even after statistical adjustments to account
for age, CVD-related deaths remain 10 to 20 times higher than in
the general population.
The high risk of CVD in end-stage renal disease is partly due
to the fact that the dialysis patient population has a higher prevalence
of conditions that are known risk factors for CVD in the general
population, such as older age, hypertension (high blood pressure),
high cholesterol levels, diabetes, and physical inactivity. The
high risk may also be partly caused by factors involved in renal
failure, including proteinuria (protein in urine), fluid retention,
irregular blood chemistries, anemia, blood clotting disorders, and
chronic inflammation.
The two most common CVD conditions seen in patients with end-stage
renal disease are coronary artery disease (CAD) and left ventricular
hypertrophy (LVH). The physical symptoms of these two conditions
may often be the same, and include chest pain, heart attack, congestive
heart failure, and arrhythmias.
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Abstracts
from Atherosclerosis - February 2012
• Effects
of Thrice Weekly Nocturnal Hemodialysis on Arterial Stiffness
• Oxidized
High-Density Lipoprotein As a Risk Factor for Cardiovascular Events in
Prevalent Hemodialysis Patients
• Study
on the Relationship between Serum 25 Hydroxyvitamin D Levels and Vascular
Calcification in Hemodialysis Patients with Consideration of Seasonal
Variation in Vitamin D Levels |
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Lipid-Lowering
Therapy in Individuals With CKD: Lessons Learned From SHARP - Free,
Full-Text Article from American Journal Of Kidney Diseases - February
2012
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Issue
in Progress Abstracts from Blood Purification - January 20, 2012
• Sudden
Cardiac Death in Hemodialysis Patients: A Comprehensive Care Approach
to Reduce Risk
• Hypertension
and Future Cardiovascular Health in Pediatric End-Stage Renal Disease
Patients
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Regression
of Left Ventricular Mass Following Conversion from Conventional Hemodialysis
to Thrice Weekly in-Center Nocturnal Hemodialysis - Provisional abstract
and full-text article (25-page
PDF) from BMC Nephrology. - January 19, 2012
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"High-Normal"
Blood Pressure Linked to Atrial Fibrillation - . Abstract from Hypertension.
- January 17, 2012 |
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Altitude
and the Risk of Cardiovascular Events in Incident US Dialysis Patients
- Advance Access Abstract from NDT - January 17, 2012
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Bisphosphonate
Therapy, Death, and Cardiovascular Events Among Female Patients With CKD:
A Retrospective Cohort Study - Article in Press abstract from American
Journal of Kidney Diseases. - January 16, 2012
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Effects
of Lowering Dialysate Sodium on Carotid Artery Atherosclerosis and Endothelial
Dysfunction in Maintenance Hemodialysis Patients - Online First Abstract
from International Urology and Nephrology - January 14, 2012
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CJASN
Express Abstracts - January 2012
• Mortality
in Kidney Disease Patients Treated with Phosphate Binders: A Randomized
Study
• Relationship
between CRP Polymorphism and Cardiovascular Events in Chinese Peritoneal
Dialysis Patients |
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Decreased
Paraoxonase One (PON One) Lactonase Activity in Hemodialyzed and Renal
Transplanted Patients. A Novel Cardiovascular Biomarker in End-Stage Renal
Disease - Advance Access abstract from NDT. - January 12, 2012
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Red
Wine-Heart Research Slammed with Fraud Charges - Article from Reuters..
- January 12, 2012
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Articles
in Press Abstracts from Journal of Nephrology - January 11, 2012
• Establishing
Goals of Volume Management in Critically Ill Patients with Renal Failure
• Risk
Factors Associated with Increased Left Ventricular Mass Index in Chronic
Kidney Disease Patients Evaluated Using Echocardiography
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Altered
Relative Concentrations of High-Energy Phosphates in Patients with Uremic
Cardiomyopathy Measured by Magnetic Resonance Spectroscopy - Advance
Access Abstract from NDT - January 11, 2012
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Prognostic
Value of Arterial Pulse Wave Velocity in Peritoneal Dialysis Patients
- Issue in Progress abstract from American Journal of Nephrology. - January
11, 2012
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Too
Much Vitamin D Could Be Harmful to Heart - Article from HealthDay.
- January 10, 2012
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Blood
Pressure Components and End-stage Renal Disease in Persons With Chronic
Kidney Disease: The Kidney Early Evaluation Program (KEEP) - Abstract
from Archives of Internal Medicine. - January 9, 2012
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Statins
Increase Diabetes Risk in Older Women - Articles from MedPage Today
and HealthDay.
- January 9, 2012
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Nation’s
Leading Medical Organizations of Physicians Support Use of Central Blood
Pressure Assessment in Effort to Improve Hypertension Care in Patients
- January 9, 2012
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Persistently
Low Intact Parathyroid Hormone Levels Predict a Progression of Aortic
Arch Calcification in Incident Hemodialysis Patients - Online First
abstract from Clinical and Experimental Nephrology. - January 5, 2012
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Increased
Gout Risk With Diuretic Use Confirmed - Article from MedPage Today.
- January 5, 2012
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Blood
Pressure Stability in Hemodialysis Patients Confers a Survival Advantage:
Results from a Large Retrospective Cohort Study - Advance Online abstract
from Kidney International. - January 4, 2012
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(Volume
Status) Is the Glass Half Empty or Half Full? - Posing from Renal
Fellow Network. - January 4, 2012
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Benefits
of Statin Therapy May Extend beyond Lowering Lipids - January 4, 2012
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Company
Claims Optical Blood Pressure Monitor Breakthrough - January 3, 2012
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When
Is the Best Moment to Assess the Ankle Brachial Index: Pre- or Post-Hemodialysis?
- Issue-in-Progress Abstract from Kidney & Blood Pressure Research
- January 3, 2012
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Articles
in Press abstracts from American Journal of Kidney Diseases - December
30, 2011
• Utilization
and Costs of Cardiovascular Disease Medications in Dialysis Patients in
Medicare Part D
• Predictive
Models for Acute Kidney Injury Following Cardiac Surgery
• Factors
Associated With Intradialytic Systolic Blood Pressure Variability
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BioTrends
ChartTrends® Report: New Study of Chronic Kidney Disease Patients
Finds That Treatment with Phosphate Binders and Active Vitamin D is Significantly
Higher When Nephrologists Suspect Arterial Calcification - December
28, 2011
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Doubt
Cast on Use of Genetic Test Before Plavix - December 28, 2011
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Improved
CVD Risk Prediction Model in Diabetes Identified - Article from HealthDay.
- December 27, 2011
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New
Blood Test May Rule Out Heart Attacks More QuicklyNew Blood Test May Rule
Out Heart Attacks More Quickly - December 27, 2011
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FDA
Okays BP Drug Combo - December 23, 2011
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Prolactin
Levels, Endothelial Dysfunction, and the Risk of Cardiovascular Events
and Mortality in Patients with CKD - CJASN Express Abstracts - December
2011
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Advance
Online Abstracts from Kidney International - December 21, 2011
• Renal
Outcomes in Hypertensive Black Patients at High Cardiovascular Risk
• The
Prevalence of and Factors Associated with Chronic Atrial Fibrillation
in Medicare/Medicaid Eligible Dialysis Patients
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Early
View Abstracts from Artificial Organs - December 21, 2011
• An
Experimental, Simplified Method for Intradialytic Cardiac Output Measurement
• Visual
Three-Dimensional Representation of Beat-to-Beat Electrocardiogram Traces
During Hemodiafiltration
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Effects
of Short- and Long-Term Hypercholesterolemia on Contrast-Induced Acute
Kidney Injury - Issue-in-Progress Abstract from American Journal of
Nephrology - December 21, 2011 |
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Home
Systolic Blood Pressure on the Morning of Dialysis Days Has Prognostic
Impact for Hypertensive Hemodialysis Patients - Online First abstract
from Clinical and Experimental Nephrology. - December 20, 2011
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Plasma
Concentration of von Willebrand Factor Predicts Mortality in Patients
on Chronic Renal Replacement Therapy - Advance Access Abstract from
NDT - December 20, 2011 |
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Treating
High Blood Pressure May Add Years to Life - Article from HealthDay.
News
release and abstract
from JAMA. - December 20, 2011
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Increase
in Resting Heart Rate over 10-Year Period Linked with Increased Risk of
Heart Disease Death - December 20, 2011
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Novartis
Ends Study of Hypertension Drug in High Risk Heart and Kidney Patients
- December 20, 2011
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Nutritional
Vitamin D Supplementation in Hemodialysis: a Potential Vascular Benefit?
- Accepted article abstract from Nephrology. - December 19, 2011
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Prevalence
of Atrial Fibrillation and Warfarin Use in Older Patients Receiving Hemodialysis
- Article in Press abstract from Journal of Nephrology. - December 16,
2011
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Achievements
in CKD-MBD Guidelines Targets: Is There a Progress in the Implementation
Practice? - Online First abstract from International Urology and Nephrology.
- December 16, 2011
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Hemodialysis
and the Risk of Stroke: a Population-based Cohort Study in Taiwan, a Country
of High Incidence of End-Stage Renal Disease - Accepted Article Abstract
from Nephrology - December 15, 2011
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Relationship
between Magnesium and Clinical Biomarkers on Inhibition of Vascular Calcification
- Issue in Progress abstract from American Journal of Nephrology. - December
15, 2011
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Contrast-Free
MRI Identifies Cardiac Ischemia - Article from MedPage Today. - December
13, 2011
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Prevalence
and Prognosis of Unrecognized Myocardial Infarctions in Chronic Kidney
Disease - Advance Access Abstract from NDT: - December 13, 2011
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Statins
Accelerate Depletion of Plaque in Arteries - Press release from the
New York University School of Medicine. - December 13, 2011
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Prevalence
and Clinical Significance of Heparin-Induced Antibodies in Chronic Hemodialysis
Patients and Cardiac Surgery Patients - Article in Press Abstract
from The International Journal of Artificial Organs - December 12, 2011
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Evaluation
of Advanced Glycation End Products Accumulation, Using Skin Autofluorescence,
in CKD and Dialysis Patients - Online First abstract from International
Urology and Nephrology. - December 10, 2011 |
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High
Plasma Pentosidine Level Is Accompanied with Cardiovascular Events in
Hemodialysis Patients - Online First abstract from Clinical and Experimental
Nephrology. - December 9, 2011
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News
Releases from the American Heart Association Continually
Updated! |
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Latest
Cardiovascular Disease News Stories - Yahoo! News Continually
Updated! |
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Latest
Hypertension News Stories - Yahoo! News Continually
Updated! |
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