RenalWEB Home Page
Last Updated 10/22/17
 

PubMed Searches

The leading cause of death for end-stage renal disease patients is cardiovascular disease (CVD).  According to the United States Renal Data System (USRDS) one uniform finding is the progressively increased representation for each cardiovascular
condition with respect to advanced CKD stage and age. In the non-CKD population, for example, only 3.6 percent of patients age 66–69 have congestive heart failure (CHF), compared to 15 percent of those age 85 and older. Among patients with Stage 4–5 CKD, these numbers reach 34 and 48 percent. CHF is a common comorbid condition in elderly patients, particularly among those with advanced CKD. 2012

The high risk of CVD in end-stage renal disease is partly due to the fact that the dialysis patient population has a higher prevalence of conditions that are known risk factors for CVD in the general population, such as older age, hypertension (high blood pressure), high cholesterol levels, diabetes, and physical inactivity. The high risk may also be partly caused by factors involved in renal failure, including proteinuria (protein in urine), fluid retention, irregular blood chemistries, anemia, blood clotting disorders, and chronic inflammation.

The two most common CVD conditions seen in patients with end-stage renal disease are coronary artery disease (CAD) and left ventricular hypertrophy (LVH).  The physical symptoms of these two conditions may often be the same, and include chest pain, heart attack, congestive heart failure, and arrhythmias.

Warning:  Changes should never be made in a patient's treatment or care based solely on the information found here.  Every patient has unique healthcare concerns and considerations and all these factors must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.


  NEWS & LATEST ARTICLES
blue ball

Free, Full-Text Articles from Kidney International - November 2017

blue ball

Synergic Impact of Vascular Calcification and Low Autonomic Tone in Mortality of Hemodialysis Patients - Abstract from Nephron. - October 2017

blue ball

Blood Pressure Targets for Hemodialysis Patients - Free, Full-Text Article from Kidney International. - October 2017

blue ball

Aldosterone Antagonist Therapy and Its Relationship with Inflammation, Fibrosis, Thrombosis, Mineral Bone Disorder and Cardiovascular Complications in Peritoneal Dialysis (PD) Patients - Free, Open Access article from International Urology and Nephrology. - October 2017

blue ball

Relationship Between Visit-to-Visit Blood Pressure Variability (BPV) and Kidney Function in Patients with Hypertension - Free, Open Access, Issue-In-Progress Article from Kidney & Blood Pressure Research. - October 19, 2017

blue ball

Articles from Medscape Nephrology (registration required, but free) - October 19, 2017

blue ball

BP Measurement in Clinical Practice: Time to SPRINT to Guideline-Recommended Protocols - JASN Express abstract. - October 19, 2017

blue ball

Newer Blood Thinners May Not Bring Higher Bleeding Risk - Article from HealthDay. Full-text article from The BMJ. - October 18, 2017

blue ball

High Blood Pressure Linked to Common Heart Valve Disorder - Press release from University of Oxford. - October 17, 2017

blue ball

Blood Pressure Parameters and Morbid and Mortal Outcomes in Nondialysis-Dependent Chronic Kidney Disease. - Published Ahead-of-Print abstract from Current Opinion in Nephrology and Hypertension. - October 16, 2017

blue ball

Insulin Dose Does Not Reflect Cardiovascular Events - Article from Renal & Urology News. - October 16, 2017

blue ball

Blood Pressure Medication Does Not Completely Restore Vascular Function - Press release from Lancaster University. - October 16, 2017

blue ball

Healthy Lifestyle Reduces Heart Attack, Stroke Risk after Gestational Diabetes, NIH Study Shows - October 16, 2017

blue ball

Physically Active White Men at High Risk for Plaque Buildup in Arteries - October 16, 2017

blue ball

Coronary Flow Reserve Is Predictive of the Risk of Cardiovascular Death Regardless of Chronic Kidney Disease Stage - Articles in Press Abstract from Kidney International. - October 14, 2017

blue ball

Low Serum Calcium Linked to Sudden Cardiac Arrest Risk - (Registration required, but free.) Article from Medscape Nephrology. - October 13, 2017

blue ball

Pregnancy-Related Heart Failure Strikes Black Women Twice As Often As Those of Other Races - October 13, 2017

blue ball

FGF23 and Left Ventricular Hypertrophy in Children with CKD - CJASN Express Abstract. - October 12, 2017

blue ball

Evaluation of the Predictive Value of the Serum Calcium-Magnesium Ratio for All-Cause and Cardiovascular Mortality in Incident Dialysis Patients - Issue-in-Progress abstract from CardioRenal Medicine. - October 11, 2017

blue ball

AI and Aerospace Models Used To Optimise Blood Flow in Veins - News release from Imperial College London. - October 10, 2017

blue ball

Frequency of Arrhythmia Symptoms and Acceptability of Implantable Cardiac Monitors in Hemodialysis Patients - Free, Open Access article from BMC Nephrology. - October 10, 2017

blue ball

New Blood Pressure Guidelines for Children - Article from The New York Times. - October 9, 2017

blue ball

The Complex Relationship among Arteriovenous Access, Heart, and Circulation - Early View abstract from Seminars in Dialysis. - October 9, 2017

blue ball

BP Accuracy Is the Ghost in the Machine - Article from Internal Medicine News. - October 7, 2017

blue ball

Scientists Find New RNA Class in Kidneys Is Linked to Hypertension - October 5, 2017

blue ball

 Oral Anticoagulation 'Reasonable' in Advanced Kidney Disease with A- Fib - Conference report from Internal Medicine News. - October 5, 2017

blue ball

Low Serum Calcium May Increase Risk of Sudden Cardiac Arrest - October 5, 2017

blue ball

Gut Bacteria Metabolism May Factor into Hypertension - October 3, 2017

blue ball

Risk of Infective Endocarditis in Patients with End Stage Kidney Disease - CJASN Express abstract. Article from Renal & Urology News. - October 3, 2017

blue ball

Addition of Novel Biomarkers for Predicting All-Cause and Cardiovascular Mortality in Prevalent Hemodialysis Patients - Free, Open Access, Early View article from Therapeutic Apheresis and Dialysis. - October 3, 2017

blue ball

FGF23 Level and Intima-Media Thickness Are Elevated From Early Stages of Chronic Kidney Disease - Early View abstract from Therapeutic Apheresis and Dialysis. - October 3, 2017

blue ball

To Screen or Not to Screen: for High Blood Pressure - Free, full-text, First Online article from Pediatric Nephrology. - October 2, 2017

blue ball

Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5 — A Systematic Review and Meta-analysis - Abstract and editorial extract from JAMA Internal Medicine. - October 1, 2017

blue ball

Still a Reasonable Goal: Targeting Cholesterol in Dialysis and Advanced Chronic Kidney Disease Patients - Free, Full-Text Editorial from Seminars In Dialysis. - September/October 2017

blue ball

Red Blood Cell Distribution Width is Associated With All-Cause and Cardiovascular Mortality in Hemodialysis Patients - Early View abstract from Therapeutic Apheresis and Dialysis. - September 29, 2017

blue ball

Troponin I Levels in Asymptomatic Hemodialysis Patients - Issue-in-Progress abstract from Blood Purification. - September 29, 2017

blue ball

High Prevalence of Cardiovascular Pathology in Children on Dialysis - (3-page pdf) News release from ERA-EDTA. - September 28, 2017

blue ball

How to Lower Blood Pressure in Real-World Primary Care Clinics - Article from Internal Medicine News. - September 28, 2017

blue ball

Halting Low-Dose Aspirin Increases Cardiovascular Events - September 28, 2017

blue ball

Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report - Article in Press Abstract from American Journal Of Kidney Diseases. - September 20, 2017

blue ball

Home Blood Pressure Monitoring for Hypertension Best Combined with Intensive Support - September 19, 2017

blue ball

Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial - Abstract from Annals of Internal Medicine. - September 19, 2017

blue ball

Early Effects of Renal Replacement Therapy on Cardiovascular Comorbidity in Children with End-Stage Kidney Disease: Findings from the 4C- T Study. - Online First abstract from Transplantation. - September 18, 2017

blue ball

Press Releases from the American Heart Association - September 17, 2017

blue ball

Eicosapentaenoic Acid as a Potential Therapeutic Approach to Reduce Cardiovascular Risk in Patients with End-Stage Renal Disease on Hemodialysis: A Review - Free, full-text, Issue-in-Progress review article from CardioRenal Medicine. - September 15, 2017

blue ball

Warfarin Use and Increased Mortality in End-Stage Renal Disease - Issue-in-Progress abstract from American Journal of Nephrology. - September 15, 2017

blue ball

Parathyroidectomy Associated With Morbidity, Mortality - Article from Renal & Urology News. - September 14, 2017

blue ball

Which Single Behavior Best Prevents High Blood Pressure? - Article from HealthDay. - September 14, 2017

blue ball

Risk of Heart Disease in Urban 'Food Deserts' Is Associated with Individual's Income Rather Than Access to Healthy Food - Press release from the American Heart Association. - September 13, 2017

blue ball

Association of Plasma Potassium with Mortality and End-Stage Kidney Disease in Patients with Chronic Kidney Disease under Nephrologist Care — The NephroTest Study - Free, Open Access article from BMC Nephrology. - September 12, 2017

blue ball

Intensive BP Control May Reduce Death Risk in CKD Patients - Article from Renal & Urology News. - September 12, 2017

blue ball

Management of Hypertension in Patients during Percutaneous Dialysis Access Interventions - Free, full-text article from the Journal of Vascular Access. - September 11, 2017

blue ball

Effectiveness of Pharmacist Interventions on Cardiovascular Risk in Patients With CKD: A Subgroup Analysis of the Randomized Controlled RxEACH Trial - Article in Press abstract from American Journal of Kidney Diseases. - September 11, 2017

blue ball

Articles from Renal & Urology News - September 11, 2017

blue ball

Free, Open Access Articles from PLOS ONE - September 6, 2017

blue ball

Diabetes and Hypertension: A Position Statement by the American Diabetes Association - Free, full-text article from Diabetes Care. - September 1, 2017

blue ball News Releases from the American Heart Association  Continually Updated!
blue ball Latest Cardiovascular Disease News Stories - Yahoo! News Continually Updated!
blue ball Latest Hypertension News Stories - Yahoo! News Continually Updated!
Top of Page


  WEB RESOURCES
blue ball Latest Scientific Journal Articles on Cardiovascular Disease
Acute and Chronic Management of Atrial Fibrillation in Patients With Late-Stage CKD - Full-text article from the American Journal of Kidney Diseases. - April 2009
Cardiovascular disease calculator and related abstract from BMJ - July 2001
Cardiovascular complications of pediatric chronic kidney disease - educational feature from Pediatric Nephrology - February 2008
Diseases & Conditions from the American Heart Association web site
Evaluation of cardiac function in the dialysis patient—a primer for the non-expert - editorial from Nephrology Dialysis Transplantation - June 2006
The Guide to Medicare Preventive Services (pdf) from the Medlearn/Centers for Medicare & Medicaid Services web site
Division for Heart Disease and Stroke Prevention: Interactive Atlas from the Centers for Disease Control and Prevention (CDC) web site
High Blood Pressure and Kidney Disease: How Are They Connected? from the Kidney & Urology Foundation of America (KUFA) web site
blue ball Hypertension - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
National Cholesterol Education Program (NCEP) (pdf) from the NIH web site. Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.
Smoothie Recipe Book for Renal and Heart Health by Victoria L Hulett JD (Author), Jennifer L Waybright RN (Contributor)
Understanding Cardiac Biomarkers in ESRD: Frequently Asked Questions and the Promise of Clinical Application - free, full-text review (43-page pdf) from Nephrology. - October 15, 2010
American Heart Association web site
American College of Cardiology web site
American Society of Hypertension web site
HeartPoint - multimedia site for patient information and education
National Heart, Lung and Blood Institute web site
Top of Page


  ESSENTIALS AND CLASSICS
Heart Failure Treatment from WebMD
High Blood Pressure and Kidney Disease from the NIDDK web site (in layman's terms)
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure - 2003
Top of Page


  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)
MEDLINE PLUS for Heart Diseases Continually Updated!
heart AND dialysis Continually Updated!
hypertension AND dialysis Continually Updated!
cardiovascular disease AND end-stage renal disease AND dialysis Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
Top of Page


  CLINICAL GUIDELINES
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update
2003 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
Treatment of Anemia in Patients With Heart Disease: A Clinical Practice Guideline From the American College of Physicians article from the Annals of Internal Medicine - December 2013
Clinical Practice Guidelines for cardiovascular disease (search result) from the  National Guideline Clearinghouse web site
Top of Page


  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative
Clinical Practice Guidelines For Chronic Kidney Disease: Table of Contents
Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients
Clinical Practice Guidelines for Hypertension and Antihypertensive Agents in Chronic Kidney Disease
Clinical Practice Guidelines for Managing Dyslipidemias in Chronic Kidney Disease


KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site


  DISCUSSION FORUM
General Dialysis Nursing Issues and Questions (No dedicated RenalWEB forum)
Top of Page


  WEB SEARCH ENGINES
Cardiovascular Disease web sites by Yahoo! Continually Updated!
Cardiovascular Disease web sites by AOL Continually Updated!
Top of Page


  INPUT / SUGGESTIONS
E-mail to RenalWEB on the Cardiovascular Disease Topic
Top of Page

 

 

Except where noted, no information within the RenalWEB web site can be copied, duplicated, or reproduced in any form without the express written consent of RenalWEB.