RenalWEB Home Page
Last Updated 3/10/19
 

PubMed Searches

The leading cause of death for end-stage renal disease patients is cardiovascular disease (CVD).  According to the United States Renal Data System (USRDS) one uniform finding is the progressively increased representation for each cardiovascular
condition with respect to advanced CKD stage and age. In the non-CKD population, for example, only 3.6 percent of patients age 66–69 have congestive heart failure (CHF), compared to 15 percent of those age 85 and older. Among patients with Stage 4–5 CKD, these numbers reach 34 and 48 percent. CHF is a common comorbid condition in elderly patients, particularly among those with advanced CKD. 2012

The high risk of CVD in end-stage renal disease is partly due to the fact that the dialysis patient population has a higher prevalence of conditions that are known risk factors for CVD in the general population, such as older age, hypertension (high blood pressure), high cholesterol levels, diabetes, and physical inactivity. The high risk may also be partly caused by factors involved in renal failure, including proteinuria (protein in urine), fluid retention, irregular blood chemistries, anemia, blood clotting disorders, and chronic inflammation.

The two most common CVD conditions seen in patients with end-stage renal disease are coronary artery disease (CAD) and left ventricular hypertrophy (LVH).  The physical symptoms of these two conditions may often be the same, and include chest pain, heart attack, congestive heart failure, and arrhythmias.

Warning:  Changes should never be made in a patient's treatment or care based solely on the information found here.  Every patient has unique healthcare concerns and considerations and all these factors must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.


  NEWS & LATEST ARTICLES
blue ball

Use of Measures of Inflammation and Kidney Function for Prediction of Atherosclerotic Vascular Disease Events and Death in Patients With CKD: Findings From the CRIC Study - Free, Full-Text Article from American Journal Of Kidney Diseases. - March 2019

blue ball

Effects of Hemodiafiltration versus Conventional Hemodialysis in Children with ESKD: The HDF, Heart and Height Study - Published Ahead of Print JASN abstract. - March 7, 2019

blue ball

A Nap a Day Keeps High Blood Pressure at Bay - Press release from the American College of Cardiology. - March 7, 2019

blue ball

Relationship between Dialytic Parameters and Reviewer Confirmed Arrhythmias in Hemodialysis Patients in the Monitoring in Dialysis Study - Free, Open Access Article from BMC Nephrology. - March 5, 2019

blue ball

Timing of Blood Pressure Medications and Intradialytic Hypotension - Early View abstract from Seminars in Dialysis. - March 5, 2019

blue ball

Use of Ambulatory Blood Pressure Monitoring in Kidney Transplant Recipients - Free, full-text, Advance Article from NDT. - March 5, 2019

blue ball

Cardiovascular Protection and Mounting Evidence for the Benefits of Intradialytic Exercise - Free, full-text, Advance Article from NDT. - March 4, 2019

blue ball

Characteristics of Coronary Artery Disease in Chronic Kidney Disease - Free, Open Access, First Online review article from Clinical and Experimental Nephrology. - March 4, 2019

blue ball

New Scientific Statement on Blood Pressure Measurement in People - Press release from the American Heart Association. Abstract from JAMA Internal Medicine. - March 4, 2019

blue ball

High Blood Pressure May Not Always Appear in Blood Pressure Readings at Doctor's Office - Press release from University of Alabama at Birmingham. - March 4, 2019

blue ball

Arterial “Inflammaging” Drives Vascular Calcification in Children on Dialysis - Free, Open Access, Articles in Press from Kidney International. - March 1, 2019

blue ball

Hyponatremia in the Dialysis Population - Free, Open Access, Article in Press from Kidney International Reports. - March 1, 2019

blue ball

Association of Blood Pressure with Clinical Outcomes in Older Adults with Chronic Kidney Disease - Free, full-text, Advance Article from Age and Aging. - February 28, 2019

blue ball

Central Venous Stenosis after Hemodialysis: Case Reports and Relationships to Catheters and Cardiac Implantable Devices - Free, full-text, Online First review article from CardioRenal Medicine. - February 27, 2019

blue ball

The Association between Long- and Intra-Dialytic Blood Pressure Variability with All-Cause Mortality in Hemodialysis Patients - Online First abstract from Blood Purification. - February 26, 2019

blue ball

Extracellular Fluid Volume Expansion, Arterial Stiffness and Uncontrolled Hypertension in Patients with Chronic Kidney Disease - Advance Article abstract from NDT. - February 25, 2019

blue ball

Absolute Risk and Risk Factors for Stroke Mortality in Patients with End-Stage Kidney Disease (ESKD): Population-based Cohort Study Using Data Linkage - Free, Open Access article from BMJ Open. - February 22, 2019

blue ball

Serum Klotho: a Potential Predictor of Cerebrovascular Disease in Hemodialysis Patients - Free, Open Access article from BMC Nephrology. - February 21, 2019

blue ball

Insulin Resistance and Chronic Kidney Disease Progression, Cardiovascular Events, and Death: Findings from the Chronic Renal Insufficiency Cohort Study - Free, Open Access article from BMC Nephrology. - February 20, 2019

blue ball

Correction of Pulmonary Hypertension with Intensive Hemodialysis: a Case Report - Early View Abstract from Hemodialysis International. - February 20, 2019

blue ball

Long Periods of Sedentary Behavior May Increase Cardiovascular Risk in Older Women - News release from the National Institutes of Health. - February 18, 2019

blue ball

Differences in Association of Lower Bone Mineral Density with Higher Coronary Calcification in Female and Male End-Stage Renal Disease Patients - Free, Open Access article from BMC Nephrology. - February 18, 2019

blue ball

Ambulatory Blood Pressures and Central Blood Pressures Are Associated with Cardiovascular Morbidity in Adolescent and Young Adult Patients Receiving Chronic Hemodialysis - First Online abstract from Pediatric Nephrology. - February 18, 2019

blue ball

A Cardiac Magnetic Resonance Imaging Study of Long-Term and Incident Hemodialysis Patients - First Online abstract from Journal of Nephrology. - February 18, 2019

blue ball

Study Finds Low Statin Use Among Kidney Disease Patients at High Risk for Cardiovascular Disease - Press release from Loyola University Health System. - February 18, 2019

blue ball

Effects of Arteriovenous Fistula on Blood Pressure in Patients With End-Stage Renal Disease: A Systematic Meta-Analysis - Free, Open Access article from the Journal of the American Heart Association. - February 15, 2019

blue ball

Variation of High-Sensitivity Troponin T Results in Patients Undergoing Continuous Renal Replacement Therapy - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - February 15, 2019

blue ball

Is Metabolic Acidosis a Friend or Foe for Cardiovascular Disease in Kidney Transplant Recipients? - Free, Full-Text, Articles in Press from American Journal Of Kidney Diseases. - February 14, 2019

blue ball

Recent Evidence for Direct Oral Anticoagulants in Chronic Kidney Disease - Published Ahead of Print abstract from Current Opinion in Nephrology and Hypertension. - February 14, 2019

blue ball

Articles in Press Abstracts and Full-Text PDFs from Kidney International Reports - February 13, 2019

blue ball

Osteocalcin (bone GLA protein) Levels, Vascular Calcifications, Vertebral Fractures and Mortality in Hemodialysis Patients with Diabetes Mellitus - First Online abstract from Journal of Nephrology. - February 13, 2019

blue ball

High Blood Pressure Hits Urban Blacks Harder - Article from HealthDay. - February 11, 2019

blue ball

The Association of the Ankle-Brachial Index, the Toe-Brachial Index, and Their Difference, with Mortality and Limb Outcomes in Dialysis Patients - Early View Abstract from Hemodialysis International. - February 8, 2019

blue ball

Vitamin D Supplementation for the Improvement of Vascular Function in Patients with Chronic Kidney Disease: a Meta-Analysis of Randomized Controlled Trials - First Online Abstract from International Urology And Nephrology. - February 8, 2019

blue ball News Releases from the American Heart Association  Continually Updated!
blue ball Latest Cardiovascular Disease News Stories - Yahoo! News Continually Updated!
blue ball Latest Hypertension News Stories - Yahoo! News Continually Updated!
Top of Page


  WEB RESOURCES
blue ball Latest Scientific Journal Articles on Cardiovascular Disease
Acute and Chronic Management of Atrial Fibrillation in Patients With Late-Stage CKD - Full-text article from the American Journal of Kidney Diseases. - April 2009
Cardiovascular disease calculator and related abstract from BMJ - July 2001
Cardiovascular complications of pediatric chronic kidney disease - educational feature from Pediatric Nephrology - February 2008
Diseases & Conditions from the American Heart Association web site
Evaluation of cardiac function in the dialysis patient—a primer for the non-expert - editorial from Nephrology Dialysis Transplantation - June 2006
Division for Heart Disease and Stroke Prevention: Interactive Atlas from the Centers for Disease Control and Prevention (CDC) web site
blue ball

Free, Full-Text, New Online Articles from the Journal of the American Medical Association - November 20, 2017

High Blood Pressure and Kidney Disease: How Are They Connected? from the Kidney & Urology Foundation of America (KUFA) web site
blue ball Hypertension - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
blue ball Medicare Preventive Services (pdf) from the Medlearn/Centers for Medicare & Medicaid Services web site
National Cholesterol Education Program (NCEP) (pdf) from the NIH web site. Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.
Smoothie Recipe Book for Renal and Heart Health by Victoria L Hulett JD (Author), Jennifer L Waybright RN (Contributor)
Understanding Cardiac Biomarkers in ESRD: Frequently Asked Questions and the Promise of Clinical Application - free, full-text review (43-page pdf) from Nephrology. - October 15, 2010
American Heart Association web site
American College of Cardiology web site
American Society of Hypertension web site
blue ball

Cardio Renal Society of America - web site Twitter #CardioRenal

HeartPoint - multimedia site for patient information and education
National Heart, Lung and Blood Institute web site
Top of Page


  ESSENTIALS AND CLASSICS
Heart Failure Treatment from WebMD
High Blood Pressure and Kidney Disease from the NIDDK web site (in layman's terms)
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure - 2003
Top of Page


  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)
MEDLINE PLUS for Heart Diseases Continually Updated!
heart AND dialysis Continually Updated!
hypertension AND dialysis Continually Updated!
cardiovascular disease AND end-stage renal disease AND dialysis Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
Top of Page


  CLINICAL GUIDELINES
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update
2003 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
blue ball Management of Heart Failure in Advancing CKD: Core Curriculum 2018 from the American Journal of Kidney Diseases
Treatment of Anemia in Patients With Heart Disease: A Clinical Practice Guideline From the American College of Physicians article from the Annals of Internal Medicine - December 2013
Top of Page


  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative
Clinical Practice Guidelines For Chronic Kidney Disease: Table of Contents
Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients
Clinical Practice Guidelines for Hypertension and Antihypertensive Agents in Chronic Kidney Disease
Clinical Practice Guidelines for Managing Dyslipidemias in Chronic Kidney Disease


KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site


  DISCUSSION FORUM
General Dialysis Nursing Issues and Questions (No dedicated RenalWEB forum)
Top of Page


  WEB SEARCH ENGINES
Cardiovascular Disease web sites by Yahoo! Continually Updated!
Cardiovascular Disease web sites by AOL Continually Updated!
Top of Page


  INPUT / SUGGESTIONS
E-mail to RenalWEB on the Cardiovascular Disease Topic
Top of Page

 

 

Except where noted, no information within the RenalWEB web site can be copied, duplicated, or reproduced in any form without the express written consent of RenalWEB.