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Last Updated 08/12/18
 

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The leading cause of death for end-stage renal disease patients is cardiovascular disease (CVD).  According to the United States Renal Data System (USRDS) one uniform finding is the progressively increased representation for each cardiovascular
condition with respect to advanced CKD stage and age. In the non-CKD population, for example, only 3.6 percent of patients age 66–69 have congestive heart failure (CHF), compared to 15 percent of those age 85 and older. Among patients with Stage 4–5 CKD, these numbers reach 34 and 48 percent. CHF is a common comorbid condition in elderly patients, particularly among those with advanced CKD. 2012

The high risk of CVD in end-stage renal disease is partly due to the fact that the dialysis patient population has a higher prevalence of conditions that are known risk factors for CVD in the general population, such as older age, hypertension (high blood pressure), high cholesterol levels, diabetes, and physical inactivity. The high risk may also be partly caused by factors involved in renal failure, including proteinuria (protein in urine), fluid retention, irregular blood chemistries, anemia, blood clotting disorders, and chronic inflammation.

The two most common CVD conditions seen in patients with end-stage renal disease are coronary artery disease (CAD) and left ventricular hypertrophy (LVH).  The physical symptoms of these two conditions may often be the same, and include chest pain, heart attack, congestive heart failure, and arrhythmias.

Warning:  Changes should never be made in a patient's treatment or care based solely on the information found here.  Every patient has unique healthcare concerns and considerations and all these factors must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.


  NEWS & LATEST ARTICLES
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Management of Heart Failure in Advancing CKD: Core Curriculum 2018 - Free, Full-Text Article from American Journal of Kidney Diseases. - August 2018

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Safe Potassium Range May Vary by CKD Stage - Article from Renal & Urology News. - August 9, 2018

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Circulating ADAMs Are Associated with Renal and Cardiovascular Outcomes in Chronic Kidney Disease Patients - Advance Articles Abstract from NDT. - August 8, 2018

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Cardionephrology: Proposal for a Futuristic Educational Approach to a Contemporary Need - Free, full-text, Online First article from CardioRenal Medicine. - August 8, 2018

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Screening for Atrial Fibrillation Comes With Many Snags - Free, full-text, New Online editorial from JAMA Internal Medicine. - August 7, 2018

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Blood Pressure Control in Conventional Hemodialysis - Early View abstract from Seminars in Dialysis. - August 6, 2018

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Pre-Dialysis Blood Pressure Measurements Misclassify Hypertension in about 1/3 of Hemodialysis Patients - (3-page pdf) Press release from the ERA/EDTA. - August 6, 2018

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The Potential of Electrocardiography for Cardiac Risk Prediction in Chronic and End-Stage Kidney Disease - Advance Article abstract from NDT. - August 6, 2018

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Female Heart Attack Patients Fare Better If ER Doc Is a Woman - Article from HealthDay. - August 6, 2018

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Detection of Atherosclerotic Cardiovascular Disease in Patients with Advanced Chronic Kidney Disease in the Cardiology and Nephrology Communities - Online First abstract from CardioRenal Medicine. - August 3, 2018

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Online First Abstracts from American Journal Of Nephrology - August 2, 2018

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Free, Full-Text, Issue-In-Progress Articles from Kidney & Blood Pressure Research - July 31, 2018

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Microsoft Files Patent Application for Eyeglasses That Gauge Blood Pressure - Article from Healthcare IT News. - July 30, 2018

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Association of Ambulatory Blood Pressure with All-Cause and Cardiovascular Mortality in Hemodialysis Patients: Effects of Heart Failure and Atrial Fibrillation - JASN Express abstract. - July 25, 2018

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Left Ventricular Strain and Dyssynchrony in Young and Middle-Aged Peritoneal Dialysis Patients and Healthy Controls: A Case-Matched Study - Online First abstract from CardioRenal Medicine. - July 25, 2018

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Intensive Blood Pressure Control May Preserve Brain Health (SPRINT MIND) - Article from HealthDay. Press releases from University of Alabama at Birmingham and the National Institutes of Health. - July 25, 2018

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Derivation and Validation of Risk Scores to Predict Cerebrovascular Mortality Among Incident Peritoneal Dialysis Patients - Free, Open Access, Issue-in-Progress article from Kidney & Blood Pressure Research. - July 23, 2018

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Why Do Kidney Disease and Heart Failure Correlate? - News brief from the American Society for Biochemistry and Molecular Biology. - July 23, 2018

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Progression of Medial Arterial Calcification In Chronic Kidney Disease - (18-page pdf) - Article in Press Abstract and Full-Text PDF from Kidney International Reports. - July 21, 2018

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Incident Atrial Fibrillation and the Risk of Stroke in Adults with Chronic Kidney Disease - CJASN Express abstract. - July 20, 2018

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Association between Intensity of Statin Therapy and Mortality in Persons with Chronic Kidney Disease - Advance Article abstract from NDT. - July 20, 2018

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Albuminuria and Allograft Failure, Cardiovascular Disease Events, and All-Cause Death in Stable Kidney Transplant Recipients: A Cohort Analysis of the FAVORIT Trial - Articles in Press Abstract American Journal of Kidney Diseases. - July 20, 2018

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Beyond Hypertension and Cardio-Renal Syndrome: The Need to Acknowledge and Incorporate Renal Disease in Cardiac Electrophysiology Trials - Free, Open Access, Issue-in-Progress editorial from American Journal of Nephrology. - July 20, 2018

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Which Anticoagulants Should Be Used for Stroke Prevention in Non-Valvular Atrial Fibrillation and Severe Chronic Kidney Disease? - Published Ahead-of-Print abstract from Current Opinion in Nephrology and Hypertension. - July 16, 2018

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Virtual Counseling Helps Lower Blood Pressure - July 16, 2018

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Death Rates from Heart Failure Higher for Women Than Men - July 16, 2018

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New Definition Means Almost Half the World's Adult Population Now Hypertensive - (Registration required, but free.) Article from Medscape Nephrology. - July 13, 2018

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Clinical Pharmacology of Oral Anticoagulants in Patients with Kidney Disease - Free, full-text CJASN Express article. - May 25, 2018

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Wireless, Intraoral Hybrid Electronics for Real-Time Quantification of Sodium Intake toward Hypertension Management - Abstract from Proceedings of the National Academy of Sciences. - May 7, 2018

blue ball News Releases from the American Heart Association  Continually Updated!
blue ball Latest Cardiovascular Disease News Stories - Yahoo! News Continually Updated!
blue ball Latest Hypertension News Stories - Yahoo! News Continually Updated!
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  WEB RESOURCES
blue ball Latest Scientific Journal Articles on Cardiovascular Disease
Acute and Chronic Management of Atrial Fibrillation in Patients With Late-Stage CKD - Full-text article from the American Journal of Kidney Diseases. - April 2009
Cardiovascular disease calculator and related abstract from BMJ - July 2001
Cardiovascular complications of pediatric chronic kidney disease - educational feature from Pediatric Nephrology - February 2008
Diseases & Conditions from the American Heart Association web site
Evaluation of cardiac function in the dialysis patient—a primer for the non-expert - editorial from Nephrology Dialysis Transplantation - June 2006
The Guide to Medicare Preventive Services (pdf) from the Medlearn/Centers for Medicare & Medicaid Services web site
Division for Heart Disease and Stroke Prevention: Interactive Atlas from the Centers for Disease Control and Prevention (CDC) web site
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Free, Full-Text, New Online Articles from the Journal of the American Medical Association - November 20, 2017

High Blood Pressure and Kidney Disease: How Are They Connected? from the Kidney & Urology Foundation of America (KUFA) web site
blue ball Hypertension - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
National Cholesterol Education Program (NCEP) (pdf) from the NIH web site. Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.
Smoothie Recipe Book for Renal and Heart Health by Victoria L Hulett JD (Author), Jennifer L Waybright RN (Contributor)
Understanding Cardiac Biomarkers in ESRD: Frequently Asked Questions and the Promise of Clinical Application - free, full-text review (43-page pdf) from Nephrology. - October 15, 2010
American Heart Association web site
American College of Cardiology web site
American Society of Hypertension web site
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Cardio Renal Society of America - web site Twitter #CardioRenal

HeartPoint - multimedia site for patient information and education
National Heart, Lung and Blood Institute web site
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  ESSENTIALS AND CLASSICS
Heart Failure Treatment from WebMD
High Blood Pressure and Kidney Disease from the NIDDK web site (in layman's terms)
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure - 2003
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  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)
MEDLINE PLUS for Heart Diseases Continually Updated!
heart AND dialysis Continually Updated!
hypertension AND dialysis Continually Updated!
cardiovascular disease AND end-stage renal disease AND dialysis Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
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  CLINICAL GUIDELINES
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update
2003 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
blue ball Management of Heart Failure in Advancing CKD: Core Curriculum 2018 from the American Journal of Kidney Diseases
Treatment of Anemia in Patients With Heart Disease: A Clinical Practice Guideline From the American College of Physicians article from the Annals of Internal Medicine - December 2013
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative
Clinical Practice Guidelines For Chronic Kidney Disease: Table of Contents
Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients
Clinical Practice Guidelines for Hypertension and Antihypertensive Agents in Chronic Kidney Disease
Clinical Practice Guidelines for Managing Dyslipidemias in Chronic Kidney Disease


KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site


  DISCUSSION FORUM
General Dialysis Nursing Issues and Questions (No dedicated RenalWEB forum)
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  WEB SEARCH ENGINES
Cardiovascular Disease web sites by Yahoo! Continually Updated!
Cardiovascular Disease web sites by AOL Continually Updated!
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  INPUT / SUGGESTIONS
E-mail to RenalWEB on the Cardiovascular Disease Topic
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