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| The leading cause of death for end-stage renal disease patients
is cardiovascular disease (CVD). In the prevalent dialysis
population, the percentage of deaths due to cardiac disease has
fallen from 45 in 1997–1999 to 39 in 2007–2009; the
percentage attributable to cardiovascular disease has declined from
50 to 42 according to the United States Renal Data System (USRDS).
This risk for CVD is about 30 times the risk in the general
population. Even after statistical adjustments to account
for age, CVD-related deaths remain 10 to 20 times higher than in
the general population.
The high risk of CVD in end-stage renal disease is partly due
to the fact that the dialysis patient population has a higher prevalence
of conditions that are known risk factors for CVD in the general
population, such as older age, hypertension (high blood pressure),
high cholesterol levels, diabetes, and physical inactivity. The
high risk may also be partly caused by factors involved in renal
failure, including proteinuria (protein in urine), fluid retention,
irregular blood chemistries, anemia, blood clotting disorders, and
chronic inflammation.
The two most common CVD conditions seen in patients with end-stage
renal disease are coronary artery disease (CAD) and left ventricular
hypertrophy (LVH). The physical symptoms of these two conditions
may often be the same, and include chest pain, heart attack, congestive
heart failure, and arrhythmias.
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Serum
Phosphorus Reduction in Dialysis Patients Treated with Cinacalcet for
Secondary Hyperparathyroidism Results Mainly from Parathyroid Hormone
Reduction - Free, full-text, Advance Access Article from Clinical
Kidney Journal. - April 11, 2013
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Why
Do People with Apple Shaped Bodies Have an Increased Risk of Kidney Disease? -
April 20, 2013
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Diuretics,
ACEIs, ARBs, and NSAIDs: A Nephrotoxic Combination - April 11,
2013
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Cardiopoietic
'Smart' Stem Cells Show Promise in Heart Failure Patients - Press
release from The Mayo Clinic. - April 10, 2013
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Enlarged
Heart No Excuse for Inactivity - (Registration required, but free.)
Article from MedPage Today. - April 10, 2013
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Increased
Night Heart Rate Is Associated with Worse Large Artery Elasticity in Chronic
Kidney Disease Patients - Online First abstract from International
Urology and Nephrology. - April 2013
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Nighttime
Blood Pressure, Systolic Blood Pressure Variability, and Left Ventricular
Mass Index in Children with Hypertension - Online First abstract from
Pediatric Nephrology. - April 2013
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Increased
Basal Nitric Oxide Amplifies the Association of Inflammation with All
Cause and Cardiovascular Mortality in Prevalent Hemodialysis Patients
- Online First abstract from International Urology and Nephrology. -
April 2013
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Predictors
of Cardiovascular Events in Hemodialysis Patients after Stress Myocardial
Perfusion Imaging - Early View abstract from Hemodialysis International. -
April 9, 2013
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Cinacalcet
Upregulates Calcium-Sensing Receptors of Parathyroid Glands in Hemodialysis
Patients - Issue-in-Progress Article from American Journal of Nephrology -
April 9, 2013
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Cardiac
Treatment Improves after Taking Page from Toyota Playbook - Article
from American Medical News. - April 8, 2013
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Nearly
30 Percent of Americans Have High Blood Pressure: CDC - Articles from
HealthDay and the CDC's MMWR. -
April 4, 2013
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Magnesium
Prevents Phosphate Induced Calcification in Human Aortic Vascular Smooth
Muscle Cells - Free, full-text article from NDT. - April 2013
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Full-Text Articles
from the British Medical Journal - April 4, 2013
• Effect
of Longer Term Modest Salt Reduction on Blood Pressure: Cochrane Systematic
Review and Meta-Analysis of Randomized Trials
• Effect of Lower
Sodium Intake on Health: Systematic Review and Meta-Analyses
• Effect of Increased
Potassium Intake on Cardiovascular Risk Factors and Disease: Systematic
Review and Meta-Analyses
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Waist
Circumference Is Associated with Carotid Intima Media Thickness in Peritoneal
Dialysis Patients - Online First abstract from International Urology
and Nephrology. - April 2013
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Hemodialysis
and Hemodiafiltration Differently Modulate Left Ventricular Diastolic
Function - Provisional abstract and full-text article (16-page
pdf) from BMC Nephrology. - April 2, 2013
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Calciphylaxis
and Sodium Thiosulfate: a Glimmer of Hope in Desperate Situation -
Early View abstract from Journal of Renal Care. - April 2, 2013
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Sevelamer:
A Phosphate Binder Friend With Benefits? - (Registration required,
but free.) Berns on Nephrology video from Medscape Nephrology. -
April 1, 2013
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FGF-23,
Vascular Calcification, and Cardiovascular Diseases in Chronic Hemodialysis
Patients - Online First abstract from International Urology and Nephrology. -
April 2013
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Diuretics
or Ultrafiltration for Acute Decompensated Heart Failure and Cardiorenal
Syndrome? - Free, full-text, Article in Press editorial from American
Journal of Kidney Diseases. - April 1, 2013
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Blood
Pressure Measurement in Peritoneal Dialysis: Which Method Is Best?
- PDI in Press Abstract - April 1, 2013
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Evaluation
of Association between Atherogenic Index of Plasma and Intima Media Thickness
of the Carotid Artery for Subclinic Atherosclerosis in Patients on Maintenance
Hemodialysis - Early View Abstract from Hemodialysis International -
April 1, 2013
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Dietary
Phosphorus Is Associated with Greater Left Ventricular Mass - Free,
full-text article from Kidney International. - April 2013
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Changes
in Left Ventricular Diastolic Function During Hemodialysis Sessions
- Article in Press abstract from American Journal of Kidney Diseases. -
April 1, 2013
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Magnesium
Prevents Phosphate Induced Calcification in Human Aortic Vascular Smooth
Muscle Cells - Free, full-text article from NDT. - April 2013
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QT
Interval in CKD and Hemodialysis Patients - Abstract from Clinical
Kidney Journal - April 2013
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Issue-in-Progress
Open Access Articles from Kidney & Blood Pressure Research -
April 2013
• Calf Bioimpedance
Spectroscopy for Determination of Dry Weight in Hemodialysis Patients:
Effects on Hypertension and Left Ventricular Hypertrophy
• Cardiovascular
Risk and Mineral Bone Disorder in Patients with Chronic Kidney Disease
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Effect
of Nonsurgical Periodontal Treatment on C-Reactive Protein Levels in Maintenance
Hemodialysis Patients - Early Online Abstract from Renal Failure -
March 28, 2013
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Blood
Pressure Recordings During Hemodialysis Access Interventions: Implications
for Acute Management - Early View abstract from Seminars in Dialysis. -
March 28, 2013
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Magnitude
of End-Dialysis Overweight is Associated with All-Cause and Cardiovascular
Mortality: A 3-Year Prospective Study - Issue-in-Progress article
from American Journal of Nephrology. - March 28, 2013
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Audit-based
Education Lowers Systolic Blood Pressure in Chronic Kidney Disease: the
Quality Improvement in CKD (QICKD) Trial Results - Free, full-text,
Advance Access article from Kidney International. - March 27, 2013
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Remote
Ischemic Preconditioning in Hemodialysis: a Pilot Study - Online First
abstract from Heart and Vessels. - March 2013
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Chelation
Little Help for Heart Disease: Study - March 26, 2013
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Coronary
Artery Calcium Score Prediction of All Cause Mortality and Cardiovascular
Events in People with Type II Diabetes: Systematic Review and Meta-Analysis
- Free, full-text article from BMJ. - March 25, 2013
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Heart
Repair Breakthroughs Replace Surgeon's Knife - Article from AP. -
March 25, 2013
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Ferric
Citrate Hydrate, a New Phosphate Binder, Prevents the Complications of
Secondary Hyperparathyroidism and Vascular Calcification - Free, Full-Text,
Issue-In-Progress Article from American Journal Of Nephrology - March
23, 2013
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Dynamic
Cardiac Dyssynchrony Is Strongly Associated with 2-Year Dialysis Adequacy
in Continuous Ambulatory Peritoneal Dialysis Patients - (15-page
pdf) - Provisional Abstract and Full-Text Article (PDF) from BMC Nephrology -
March 23, 2013
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Atrial
Fibrillation and Warfarin Use in Haemodialysis Patients: An Individualized
Holistic Approach is Important in Stroke Prevention - Accepted Article
abstract and full-text (19-page
pdf) from Nephrology. - March 22, 2013
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Nicotinic
Acid and Nicotinamide: A Review of Their Use for Hyperphosphatemia in
Dialysis Patients - Early View abstract from Pharmacotherapy. -
March 21, 2013
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Ultrafiltration
in Heart Failure with Cardiorenal Syndrome - Correspondence from the
New England Journal of Medicine - March 21, 2013
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The
Malnutrition-Inflammation-Depression-Arteriosclerosis Complex Is Associated
with an Increased Risk of Cardiovascular Disease and All-Cause Death in
Chronic Hemodialysis Patients - Issue in Progress abstract from Nephron
Clinical Practice. - March 2013
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Novel
Filtration Markers as Predictors of All-Cause and Cardiovascular Mortality
in US Adults - Articles in Press Abstract from American Journal Of
Kidney Diseases - March 21, 2013
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Disparities
in Antihypertensive Medication Adherence in Adolescents - Online First
abstract from Pediatric Nephrology. - March 2013
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Arterial
Disease in Chronic Kidney Disease - (Registration required, but free.)
Article from Heart via Medscape Nephrology. - March 2013
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Anxiety,
Depression May Triple Risk of Death for Heart Patients: Study - Article
from HealthDay. Online
First article from the Journal of the American Heart Association. -
March 19, 2013
"(An expert)... agreed anxiety and depression are most lethal when
they co-exist."
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Effects
of Increasing Diffusive Sodium Removal on Blood Pressure Control in Hemodialysis
Patients with Optimal Dry Weight - Free, full-text, Issue in Progress
article from Blood Purification. - March 19, 2013
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Clinical
Audit Improves Hypertension Control in Hemodialysis Patients - Articles
in Press Abstract from International Journal of Artificial Organs -
March 18, 2013
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Obese
Heart Patients 'Do Better' - Article from the BBC. - March 16,
2013
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Arterial
Stiffness Depends on Serum Ionized Calcium Levels During Dialysis With
Regional Citrate Anticoagulation - Early View abstract from Artificial
Organs. - March 15, 2013
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Importance
of High-Density Lipoprotein Quality: Evidence from Chronic Kidney Disease
- Published Ahead-of-Print abstract From Current Opinion in Nephrology
and Hypertension - March 10, 2013
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News
Releases from the American Heart Association Continually
Updated! |
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Latest
Cardiovascular Disease News Stories - Yahoo! News Continually
Updated! |
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Latest
Hypertension News Stories - Yahoo! News Continually
Updated! |
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