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Last Updated 10/21/18
 

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The leading cause of death for end-stage renal disease patients is cardiovascular disease (CVD).  According to the United States Renal Data System (USRDS) one uniform finding is the progressively increased representation for each cardiovascular
condition with respect to advanced CKD stage and age. In the non-CKD population, for example, only 3.6 percent of patients age 66–69 have congestive heart failure (CHF), compared to 15 percent of those age 85 and older. Among patients with Stage 4–5 CKD, these numbers reach 34 and 48 percent. CHF is a common comorbid condition in elderly patients, particularly among those with advanced CKD. 2012

The high risk of CVD in end-stage renal disease is partly due to the fact that the dialysis patient population has a higher prevalence of conditions that are known risk factors for CVD in the general population, such as older age, hypertension (high blood pressure), high cholesterol levels, diabetes, and physical inactivity. The high risk may also be partly caused by factors involved in renal failure, including proteinuria (protein in urine), fluid retention, irregular blood chemistries, anemia, blood clotting disorders, and chronic inflammation.

The two most common CVD conditions seen in patients with end-stage renal disease are coronary artery disease (CAD) and left ventricular hypertrophy (LVH).  The physical symptoms of these two conditions may often be the same, and include chest pain, heart attack, congestive heart failure, and arrhythmias.

Warning:  Changes should never be made in a patient's treatment or care based solely on the information found here.  Every patient has unique healthcare concerns and considerations and all these factors must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.


  NEWS & LATEST ARTICLES
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Free, Full-Text Articles from the Clinical Journal of the American Society Of Nephrology - October 2018

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Dietary Approach to Stop Hypertension (DASH) Diet and Risk of Renal Function Decline and All-Cause Mortality in Renal Transplant Recipients - Free, Full-Text Article from American Journal of Transplantation. - October 2018

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Why Does Diabetes Cause Heart Failure? - Press release from Loyola University. - October 18, 2018

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A No-Pain Gain to Combat Hypertension: UT Research Finds Way to Mimic Exercise's Blood Pressure Lowering Effects - Press release from the University of Toledo. - October 17, 2018

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Novel Initiative Taps Power of Black Churches to Control HTN - (Registration required, but free.) Article from Medscape Nephrology. - October 16, 2018

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Cost of Blood Pressure Drug Surges in U.S. after Recall - Article from Reuters. - October 16, 2018

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Gut Microbial Product Predicts Cardiovascular Risk in Chronic Kidney Disease Patients - Online First abstract from American Journal of Nephrology. - October 16, 2018

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Kidney Function, ACE-Inhibitor/Angiotensin Receptor Blocker Use, and Survival Following Hospitalization for Heart Failure: A Cohort Study - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - October 15, 2018

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Associations of Sclerostin with Carotid Artery Atherosclerosis and All-Cause Mortality in Chinese Patients Undergoing Maintenance Hemodialysis - Free, Open Access Article from BMC Nephrology. - October 12, 2018

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Truncal Adiposity Influences High-Density Lipoprotein Cholesterol Levels and Cardiovascular Events in Hemodialysis Patients - Articles in Press Abstract from Journal Of Renal Nutrition. - October 12, 2018

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Public Comment Period Open Medicare National Coverage Determination on Ambulatory Blood Pressure Monitoring - Notice from CMS. - October 9, 2018

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Dietary Fiber Intake: Its Relation With Glycation End Products and Arterial Stiffness in End-Stage Renal Disease Patients - Article in Press abstract from Journal of Renal Nutrition. - October 9, 2018

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Gene Mutation Points to New Way to Fight Diabetes, Obesity, Heart Disease - News release from the National Institutes of Health. - October 9, 2018

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Faith-Based Approach to Changing Lifestyle Lowers Blood Pressure - Press releases from the American Heart Association and NYU Langone Health. - October 9, 2018

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Neprilysin Inhibition and Effects on Kidney Function and Surrogates of Cardiovascular Risk in Chronic Kidney Disease - Free, full-text article from Circulation. - October 8, 2018

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Anti-Hypertensive Agents and Removal by Hemodialysis - Posting from the NephronPower blog. - October 8, 2018

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Frequency and Associations of Prescription Nonsteroidal Anti-inflammatory Drug Use Among Patients With a Musculoskeletal Disorder and Hypertension, Heart Failure, or Chronic Kidney Disease - Online First abstract from JAMA Internal Medicine. - October 8, 2018

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Using Personal Data to Predict Blood Pressure - Press release from UCSD. - October 4, 2018

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Diet Rich in Fried and Processed Foods Linked to Increased Hypertension in Black Americans - News release from the National Institutes of Health. - October 3, 2018

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Novel Inhibitor of Vascular Calcification Tested in Trial of Hemodialysis Patients - Press release from the British Journal of Clinical Pharmacology. - October 3, 2018

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First-Time-in-Human Randomized Clinical Trial in Healthy Volunteers and Hemodialysis Patients with SNF472, a Novel Inhibitor of Vascular Calcification - Free, Open Access, Early View article from British Journal of Clinical Pharmacology. - October 2, 2018

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Southern Diet Is Top Factor Associated with Higher Risk of High Blood Pressure among Black Adults - Press release from the Journal of the American Medical Association. - October 2, 2018

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Articles from Medscape Nephrology (registration required, but free) - October 2, 2018

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Hypertensive Crisis in Children and Adolescents - First Online Abstract from Pediatric Nephrology. - October 1, 2018

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Direct-Acting Oral Anticoagulants and Warfarin Examined in Patients with AF and Multiple Comorbidities - News brief from NEJM Journal Watch. - October 1, 2018

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Free, Full-Text Articles from September 2018 Issue of Advances in Chronic Kidney Disease - September 2018

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Gender Differences in Plasma Ghrelin Levels in Hemodialysis Patients - Early View Abstract from Therapeutic Apheresis and Dialysis. - September 27, 2018

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Split Decision on Renal Denervation for Resistant Hypertension - (Registration required, but free.) Article from Medscape Nephrology. - September 27, 2018

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CKD Associated With Increased Inter-Arm BP Difference - Article from Renal & Urology News. - September 26, 2018

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Topic Discussion: CABG (off pump vs on pump) and AKI - Posting from the NephronPower blog. - September 25, 2018

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Diastolic Dysfunction, an Underestimated New Challenge in Dialysis - Early View abstract from Therapeutic Apheresis and Dialysis. - September 25, 2018

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Amarin Fish Oil Capsule Shows Dramatic Benefit for Cardiovascular Patients, Potentially Upending Market - Article from STAT. - September 24, 2018

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Abdominal Aortic Calcification Can Predict All Cause Mortality and CV Events in Dialysis Patients: a Systematic Review and Meta-Analysis - Free, Open Access Article from PLOS ONE. - September 21, 2018

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Statin Use in Advanced CKD Lowers Death Risk - Article from Renal & Urology News. - September 21, 2018

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Association of Low Serum Potassium Levels and Risk for All-Cause Mortality in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis - Early View Abstract from Therapeutic Apheresis and Dialysis. - September 21, 2018

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Early Hypertension and Diabetes after Living Kidney Donation: A National Cohort Study - Online First Abstract from Transplantation. - September 21, 2018

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First Blood Pressure Monitor with Cellular Connectivity Now Available in U.S. - September 21, 2018

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Free, Open Access, Online First Articles from Kidney & Blood Pressure Research - September 20 - October 4, 2018

blue ball News Releases from the American Heart Association  Continually Updated!
blue ball Latest Cardiovascular Disease News Stories - Yahoo! News Continually Updated!
blue ball Latest Hypertension News Stories - Yahoo! News Continually Updated!
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  WEB RESOURCES
blue ball Latest Scientific Journal Articles on Cardiovascular Disease
Acute and Chronic Management of Atrial Fibrillation in Patients With Late-Stage CKD - Full-text article from the American Journal of Kidney Diseases. - April 2009
Cardiovascular disease calculator and related abstract from BMJ - July 2001
Cardiovascular complications of pediatric chronic kidney disease - educational feature from Pediatric Nephrology - February 2008
Diseases & Conditions from the American Heart Association web site
Evaluation of cardiac function in the dialysis patient—a primer for the non-expert - editorial from Nephrology Dialysis Transplantation - June 2006
The Guide to Medicare Preventive Services (pdf) from the Medlearn/Centers for Medicare & Medicaid Services web site
Division for Heart Disease and Stroke Prevention: Interactive Atlas from the Centers for Disease Control and Prevention (CDC) web site
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Free, Full-Text, New Online Articles from the Journal of the American Medical Association - November 20, 2017

High Blood Pressure and Kidney Disease: How Are They Connected? from the Kidney & Urology Foundation of America (KUFA) web site
blue ball Hypertension - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
National Cholesterol Education Program (NCEP) (pdf) from the NIH web site. Third Report of the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults.
Smoothie Recipe Book for Renal and Heart Health by Victoria L Hulett JD (Author), Jennifer L Waybright RN (Contributor)
Understanding Cardiac Biomarkers in ESRD: Frequently Asked Questions and the Promise of Clinical Application - free, full-text review (43-page pdf) from Nephrology. - October 15, 2010
American Heart Association web site
American College of Cardiology web site
American Society of Hypertension web site
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Cardio Renal Society of America - web site Twitter #CardioRenal

HeartPoint - multimedia site for patient information and education
National Heart, Lung and Blood Institute web site
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  ESSENTIALS AND CLASSICS
Heart Failure Treatment from WebMD
High Blood Pressure and Kidney Disease from the NIDDK web site (in layman's terms)
The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure - 2003
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  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)
MEDLINE PLUS for Heart Diseases Continually Updated!
heart AND dialysis Continually Updated!
hypertension AND dialysis Continually Updated!
cardiovascular disease AND end-stage renal disease AND dialysis Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
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  CLINICAL GUIDELINES
AHA Guidelines for Primary Prevention of Cardiovascular Disease and Stroke: 2002 Update
2003 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
blue ball Management of Heart Failure in Advancing CKD: Core Curriculum 2018 from the American Journal of Kidney Diseases
Treatment of Anemia in Patients With Heart Disease: A Clinical Practice Guideline From the American College of Physicians article from the Annals of Internal Medicine - December 2013
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative
Clinical Practice Guidelines For Chronic Kidney Disease: Table of Contents
Clinical Practice Guidelines for Cardiovascular Disease in Dialysis Patients
Clinical Practice Guidelines for Hypertension and Antihypertensive Agents in Chronic Kidney Disease
Clinical Practice Guidelines for Managing Dyslipidemias in Chronic Kidney Disease


KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site


  DISCUSSION FORUM
General Dialysis Nursing Issues and Questions (No dedicated RenalWEB forum)
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  WEB SEARCH ENGINES
Cardiovascular Disease web sites by Yahoo! Continually Updated!
Cardiovascular Disease web sites by AOL Continually Updated!
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  INPUT / SUGGESTIONS
E-mail to RenalWEB on the Cardiovascular Disease Topic
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