RenalWEB Home Page
Last Updated 09/23/18

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Untangling Mesoamerican Nephropathy - Free, Full-Text Article from American Journal Of Kidney Diseases. - October 2018

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Free, Full-Text Articles from Clinical and Experimental Nephrology - October 2018

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Risk of Colorectal Cancer in Chronic Kidney Disease: A Systematic Review and Meta-Analysis - Abstract from Journal of Clinical Gastroenterology. - October 2018

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Free, Full-Text Articles from American Journal Of Kidney Diseases - September 2018

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Free, Full-Text Articles from Kidney International - September 2018

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Certain Factors Linked with Kidney Function Recovery in Children on Dialysis - Press release and CJASN Express abstract from the American Society of Nephrology. - September 20, 2018

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Study Reveals a Promising Alternative to Corticosteroids in Acute Renal Failure Treatment - Press release from São Paulo Research Foundation (FAPESP). - September 20, 2018

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Free, Open Access Articles from BMC Nephrology - September 20, 2018

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Ovary Removal Linked to Kidney Disease - Article from HealthDay. CJASN Express abstract. Press release from the Mayo Clinic. - September 19, 2018

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Sedentary Behavior and CKD - Posting from the AJKD blog. - September 19, 2018

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A Practical Guide for Treatment of Rapidly Progressive ADPKD with Tolvaptan - JASN Express abstract. - September 2018

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Topic Discussion: Common Nephrotoxic Drugs and Their Mode of Enteries - Posting from the NephronPower blog. - September 18, 2018

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Deleterious Effects of Dialysis Emergency Start, Insights from the French REIN Registry - Free, Open Access Article from BMC Nephrology. - September 17, 2018

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Study Reveals the Current Rates of Diagnosed Type 1 and Type 2 Diabetes in American Adults - Press release from the University of Iowa. - September 17, 2018

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Kidney IDEAS: The Future OF Renal Replacement Therapy - Part 2 - Posting from the KidneyViews blog. - September 13, 2018

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Study: Kidney Stones Have Distinct Geological Histories - September 13, 2018

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Incremental Health Care Costs Associated With Food Insecurity and Chronic Conditions Among Older Adults - (Registration required, but free.) Article from Preventing Chronic Disease via Medscape Nephrology. - September 13, 2018

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New Anticoagulants in Chronic Kidney Disease: A Beacon in the Darkness - Posting from the AJKD blog. - September 12, 2018

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Gadolinium Retention After Contrast-Enhanced MRI - New Online viewpoint article from the Journal of the American Medical Association. - September 12, 2018

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Acute Critical Illness Increases Risk of Kidney Complications and Death - Press release and free, full-text article from Canadian Medical Association Journal. - September 10, 2018

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The Spectrum of Chronic Kidney Disease in China: a National Study Based on Hospitalized Patients from 2010 to 2015 - Accepted Articles Abstract from Nephrology. - September 9, 2018

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Certain Environmental Pollutants May Contribute to Poor Kidney Health - Press release and CJASN Express abstract from the American Society of Nephrology. - September 7, 2018

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Prognostic Significance of Asymptomatic Brain Natriuretic Peptide Elevation at Nephrology Referral in Patients with Chronic Kidney Disease - Online First abstract from American Journal of Nephrology. - September 7, 2018

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Kidney IDEAs: the Future of Renal Replacement Therapy - Part 1 - Posting from the KidneyViews blog. - September 6, 2018

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Diabetes Develops At a Higher Rate in the CKD Population - Article from Renal & Urology News. - September 6, 2018

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NIH Grant Will Aid Research in Preventing Kidney Failure - Press release from Louisiana State University. - September 5, 2018

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Acute Kidney Injury Following Coronary Angiography: a Nationwide Study of Incidence, Risk Factors and Long-Term Outcomes - First Online abstract from Journal of Nephrology. - September 5, 2018

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13 Most Common (Non-Dialysis) Kidney Disease Symptoms Have Been Distilled by Researchers - Article from Nursing Times. - September 4, 2018

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Thiamine Status in End-Stage Chronic Kidney Disease Patients: a Single-Center Study - First Online abstract from International Urology and Nephrology. - September 4, 2018

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Point-of-Care Ultrasound in End-Stage Kidney Disease: beyond Lung Ultrasound - Published Ahead-of-Print abstract from Current Opinion in Nephrology and Hypertension. - September 3, 2018

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Acute Kidney Injury and Chronic Kidney Disease in the Elderly and Polypharmacy - Online First abstract from Blood Purification. - September 3, 2018

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Acute Kidney Injury in Critically Ill Patients: A Prospective Randomized Study of Tidal Peritoneal Dialysis Versus Continuous Renal Replacement Therapy - Free, Full-Text, Article from Therapeutic Apheresis and Dialysis. - August 2018

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How Does Continuous Renal Replacement Therapy Affect Septic Acute Kidney Injury? - Free, full-text, Online First in-depth review from Blood Purification. - August 31, 2018

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Can Drinking More Water Forestall CKD Progression? It's Complicated - (Registration required, but free.) Article from Medscape Nephrology. - August 30, 2018

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Chronic Kidney Disease Progression in Kidney Transplant Recipients: a Focus on Traditional Risk Factors - Accepted Article abstract and full-text article (23-page pdf) from Nephrology. - August 30, 2018

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Standardizing Total Kidney Volume Measurements for Clinical Trials of Autosomal Dominant Polycystic Kidney Disease - Free, full-text, Advance Article from Clinical Kidney Journal. - August 29, 2018

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Association of Self-Reported Physical Function with Survival in Patients with Chronic Kidney Disease - Free, full-text, Advance Article from Clinical Kidney Journal. - August 28, 2018

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Increased Mortality Rate after Hospitalization Among Chronic Hemodialysis Patients: A Prospective Cohort Study - Online First abstract from Nephron. - August 28, 2018

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Assessing Renal Recovery after Acute Kidney Injury: Can Biomarkers Help? - Free, full-text, Online First mini-review from Nephron. - August 28, 2018

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The Validity of Drug Effects on Proteinuria, Albuminuria, Serum Creatinine, and Estimated GFR as Surrogate End Points for ESKD: A Systematic Review - Free, full-text, Article in Press from American Journal of Kidney Diseases. - August 24, 2018

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Why Polluted Air May Be a Threat to Your Kidneys - Press release from the University of Michigan. - August 24, 2018

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Medical Costs Associated with Chronic Kidney Disease Progression in an Asian Population with Type 2 Diabetes Mellitus - Accepted Article abstract from Nephrology. - August 24, 2018

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Overview of the 2017 KDIGO CKD-MBD Update: Practice Implications for Adult Hemodialysis Patients - Free, full-text, Article in Press from Journal of Renal Nutrition. - August 23, 2018

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Care Access Not Main Driver of Racial Disparities in Kidney Disease - Press release from the University of Pennsylvania School of Medicine. - August 23, 2018

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Risk of ESRD and Mortality in Kidney and Bladder Stone Formers - Articles in Press Abstract from American Journal Of Kidney Diseases. - August 23, 2018

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Serum Potassium As a Predictor of Adverse Clinical Outcomes in Patients with Chronic Kidney Disease: New Risk Equations Using the UK Clinical Practice Research Datalink - Free, Open Access Article from BMC Nephrology. - August 22, 2018

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Multi-Million-Dollar Grant to Grow Kidney Research - Press release from University of California San Diego Health. - August 21, 2018

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Nanoparticle Targets Kidney Disease for Drug Delivery - Press release from the University of Southern California. - August 21, 2018

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Could Vitamin B3 Treat Acute Kidney Injury? - Press release from Beth Israel Deaconess Medical Center. - August 20, 2018

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Kidney Disease Is a Killer. More Precise Classification Can Help Tame It - Opinion piece from STAT. - August 20, 2018

Editor's note: Shouldn't Fresenius Medical Care have a renal rehabilitation program first? Why are they focusing on future patients? Shouldn't FMC have had a renal rehabilitation program from the start?

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A Review of Clinical Characteristics and Genetic Backgrounds in Alport Syndrome - Free, Open Access, First Online article from Clinical and Experimental Nephrology. - August 20, 2018

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Renal Disorders in Pregnancy: Core Curriculum 2019 - Free, full-text, Article in Press from American Journal of Kidney Diseases. - August 16, 2018

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Characteristics and Outcomes of Patients With Systemic Sclerosis (Scleroderma) Requiring Renal Replacement Therapy in Europe: Results From the ERA-EDTA Registry - Articles in Press Abstract from American Journal Of Kidney Diseases. - August 16, 2018

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Blood Test Could Detect Kidney Cancer Up to Five Years Prior to Clinical Diagnosis - August 16, 2018

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Hemodynamic Impact of the Connection to Continuous Renal Replacement Therapy in Critically Ill Children - Free, Open Access, First Online article from Pediatric Nephrology. - August 15, 2018

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FDA Approves New Treatment for a Rare Genetic Disorder, Fabry Disease - FDA news release. - August 10, 2018

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Topic Discussion: ECMO and the Kidney - Posting from the NephronPower blog. - August 10, 2018

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Medical Nutrition Therapy Provided by RDNs Can Help Slow the Progression of Chronic Kidney Disease - Press release from the Academy of Nutrition and Dietetics. - August 9, 2018

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Renal Regeneration after Acute Kidney Injury - Free, full-text article from Nephrology. - March 25, 2018

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

blue ball CKD Booklet for Professional - 7.0 edition 2015
Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

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Clinical Pharmacokinetics in Kidney Disease — Fundamental Principles - Free, Full-Text, CJASN Express Articles - June 2018

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
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ERA-EDTA Registry Annual Report (covers 2015 data) - (150-page pdf) The ERA-EDTA Registry collects data on renal replacement therapy (RRT) via the national and regional renal registries in Europe and countries bordering the Mediterranean Sea. For this 2015 Annual Report data sets from 52 national or regional renal registries in 36 countries were used.

2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
blue ball Infographic: Polycystic kidney disease (PKD) from the Mayo Clinic News Network
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
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Mayo Clinic Minute: Understanding Chronic Kidney Disease - 1-minute video.

blue ball Mayo Clinic Q and A: Understanding chronic kidney disease from the Mayo Clinic web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
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new Renal Disorders in Pregnancy: Core Curriculum 2019 - Free, full-text, Article in Press from American Journal of Kidney Diseases. - August 16, 2018

10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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UK's "Think Kidneys" Campaign - 2018

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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

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K/ DOQI Main Page on the National Kidney Foundation web site

 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

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Eleven New Indicators of CKD Have Been Added to the Resources on the CDC's CKD Surveillance System Website - April 2018

View all indicators.

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2017 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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