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Last Updated 1/13/19

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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The Case for a Bariatric-Centered Approach to Chronic Kidney Disease Care - Published Ahead of Print CJASN perspective piece. - January 2019

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Patients,' Nephrologists,' and Predicted Estimations of ESKD Risk - Published Ahead of Print CJASN Abstract. - January 2019

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Free, Full-Text Articles from Kidney International - January 2019

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Projecting ESRD Incidence and Prevalence in the United States through 2030 - Published Ahead of Print abstract and editorial extract from the Journal of the American Society of Nephrology. - January 2019

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Incident Type 2 Diabetes Among Individuals With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study - Free, Full-Text Article from American Journal Of Kidney Diseases. - January 2019

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Low Use of Routine Medical Care among African Americans with High CKD Risk: the Jackson Heart Study - Free, Open Access Article from BMC Nephrology. - January 10, 2019

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Prediction of Chronic Kidney Disease Progression by Magnetic Resonance Imaging: Where Are We? - Free, full-text, Online First editorial from American Journal of Nephrology. - January 10, 2019

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Press Releases from the National Kidney Foundation - January 9, 2019

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Free, Open Access Articles from BMC Nephrology - January 9, 2019

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Landmark Trials in Lupus Nephritis: Look How Far We've Come! - Posting from the Renal Fellow Network blog. - January 9, 2019

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Analysis of Nationwide Data to Determine the Incidence and Diagnosed Prevalence of Autosomal Dominant Polycystic Kidney Disease in the USA: 2013–2015 - Free, Open Access, Online First article from Kidney Diseases. - January 9, 2019

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Sepsis Associated Acute Kidney Injury - Free, full-text article from The BMJ. - January 9, 2019

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Advocacy for Broader Inclusion to Combat the Global Threat of Acute Kidney Injury - Free, full-text, Advance Article from NDT. - January 8, 2019

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New Diabetes Drugs Solidify Their Cardiovascular and Renal Benefits - Conference coverage from Internal Medicine News. - January 7, 2019

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Personalized Vaccine to Be Tested for the First Time in Patients with Kidney Cancer - Press release from Dana-Farber Cancer Institute. - January 7, 2019

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Progress in the Understanding of Polycystic Kidney Disease - Tweet with link to article from Nature Reviews Nephrology. - January 4, 2019

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Free, Open Access Articles from BMC Nephrology - January 3, 2019

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Articles in Press Abstracts from American Journal of Kidney Diseases - December 29, 2018

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Sugar Sweetened Beverage Pattern Linked to Higher Kidney Disease Risk - Press release from the American Society of Nephrology. Article from HealthDay.  - December 27, 2018
Free, full-text, Published Ahead of Print CJASN articles:

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Researchers Discover Kidney Disease Gene Affects More Populations Than Previously Thought - Press release from Mount Sinai School of Medicine. Correspondence extract from the New England Journal of Medicine. - December 27, 2018

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Relationship between Caffeine Intake and Autosomal Dominant Polycystic Kidney Disease Progression: a Retrospective Analysis Using the CRISP Cohort - Free, Open Access Article from BMC Nephrology. - December 27, 2018

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For Patients with Kidney Disease, Genetic Testing May Soon Be Routine - Press release from Columbia University Irving Medical Center. Recently Published abstract from The New England Journal of Medicine. - December 26, 2018

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Causes and Risk Factors for Acute Dialysis Initiation among Patients with End-Stage Kidney Disease — A Large Retrospective Observational Cohort Study - Free, full-text, Advance Article from Clinical Kidney Journal. - December 22, 2018

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Study Compares Scheduled vs. Emergency-Only Dialysis among Undocumented Immigrants - Press release, New Online full-text article and editorial from JAMA Internal Medicine. - December 21, 2018

"Efforts to limit health care access to contain costs not only compromise our moral compass but also lead to negative financial and health consequences. Compassionate care is equitable, high quality, comprehensive, affordable, and accessible to all, regardless of immigration status."

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Kidney Patients Are the Most Complex Patients - Press release from ERA-EDTA. - December 21, 2018

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ARBs/ACEIs After Acute Kidney Injury: Balancing Tradeoffs - Article from Medscape Nephrology (registration required, but free). - December 20, 2018

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Development of an International Standard Set of Value-Based Outcome Measures for Patients With Chronic Kidney Disease: A Report of the International Consortium for Health Outcomes Measurement (ICHOM) CKD Working Group - Free, full-text, Article in Press from American Journal of Kidney Diseases. - December 20, 2018

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Low-Carbohydrate High-Protein Diet is Associated With Increased Risk of Incident Chronic Kidney Diseases Among Tehranian Adults - Articles in Press Abstract from Journal Of Renal Nutrition. - December 19, 2018

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The Efficacy of Long-Term Treatment with Tolvaptan to Prolong the Time until Dialysis Initiation in Patients with Chronic Kidney Disease and Heart Failure - Accepted Article abstract from Therapeutic Apheresis and Dialysis. - December 19, 2018

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Kidney Failure on the Rise in Australians under 50 with Type 2 Diabetes - Press release from Baker Heart and Diabetes Institute. - December 19, 2018

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Renal Biopsy Draft Guidelines: For Comment - Notice from Kidney Health Australia - Caring for Australians with Renal Impairment (KHA-CARI). - December 2018

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Trends in Incidence of ESKD in People With Type 1 and Type 2 Diabetes in Australia, 2002-2013 - Article in Press abstract from American Journal of Kidney Diseases. - December 19, 2018

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Why a Kidney Disease Drug Approval in China Is Just the Start for This S.F. Company (FibroGen) - Articles from San Francisco Business Times and FiercePharma. News brief from Seeking Alpha. - December 18, 2018

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Effects of Probiotic Supplements on the Progression of Chronic Kidney Disease: a Meta-Analysis - Accepted Article abstract from Nephrology. - December 18, 2018

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Universal Care for Kidney Diseases: Sustainable Development or Path to Financial Ruin? - (9-page PDF) Free, full-text, Article in Press from Kidney International Reports. - December 17, 2018

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Serious Kidney Injury Common during Cancer Chemotherapy - Article from Reuters Health. - December 17, 2018

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Dr. Jonathan Rich and Nephrologist, Dr. Robert Greenwell Discuss Kidney Stones - Press release from Mercy Medical Center (Baltimore). - December 17, 2018

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Year in Review Abstracts from Nature Reviews Nephrology - December 10-17, 2018

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Do Neprilysin Inhibitors Have a Role in Patients With CKD? - Article from Medscape Nephrology (registration required, but free). - December 14, 2018

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Diagnostic Accuracy of Frailty Screening Methods in Advanced Chronic Kidney Disease - Online First abstract from Nephron. - December 14, 2018

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Latest News from UCSF's The Kidney Project - Facebook page update. The Kidney Project web site. - December 3, 2018

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Early View Abstracts from Oral Diseases - November 8, 2018

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

blue ball CKD Booklet for Professional - 7.0 edition 2015
blue ball new Chronic Kidney Disease Change Package from The National Kidney Foundation web site
Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
blue ball Chronic Kidney Disease from the American Kidney Fund web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

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Clinical Pharmacokinetics in Kidney Disease — Fundamental Principles - Free, Full-Text, CJASN Express Articles - June 2018

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
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ERA-EDTA Registry Annual Report (covers 2015 data) - (150-page pdf) The ERA-EDTA Registry collects data on renal replacement therapy (RRT) via the national and regional renal registries in Europe and countries bordering the Mediterranean Sea. For this 2015 Annual Report data sets from 52 national or regional renal registries in 36 countries were used.

2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
blue ball Guide to Dialysis and Kidney Disease - from the National Council for Aging Care
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
blue ball Infographic: Polycystic kidney disease (PKD) from the Mayo Clinic News Network
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
blue ball Management of Acute Kidney Injury: Core Curriculum 2018 from the American Journal of Kidney Diseases
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Mayo Clinic Minute: Understanding Chronic Kidney Disease - 1-minute video.

blue ball Mayo Clinic Q and A: Understanding chronic kidney disease from the Mayo Clinic web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
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Renal Disorders in Pregnancy: Core Curriculum 2019 - Free, full-text, Article in Press from American Journal of Kidney Diseases. - August 16, 2018

10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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UK's "Think Kidneys" Campaign - 2018

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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

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K/ DOQI Main Page on the National Kidney Foundation web site

 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

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Eleven New Indicators of CKD Have Been Added to the Resources on the CDC's CKD Surveillance System Website - April 2018

View all indicators.

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2018 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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