RenalWEB Home Page
Last Updated 09/10/17

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Early Mortality Associated with Inpatient versus Outpatient Hemodialysis Initiation in a Large Cohort of US Veterans with Incident End-Stage Renal Disease - Abstract from Nephron. - September 2017

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SGLT-2 Inhibition: A Potential New Treatment for Diabetic Kidney Disease? - Free, Full-Text Article from Nephron. - September 2017

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Free, Full-Text Articles from American Journal of Kidney Diseases - September 2017

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Free, Full-Text Articles from Kidney International - September 2017

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Patients Double-Seropositive for ANCA and Anti-GBM Antibodies Have Varied Renal Survival, Frequency of Relapse, and Outcomes Compared to Single-Seropositive Patients - Free, Full-Text Article from Kidney International. - September 2017

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Predictors of Acute Renal Injury Study (PARIS) among HIV-Positive Individuals: Design and Methods - Free, Open Access Article from BMC Nephrology. - September 7, 2017

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Bristol-Myers Stops Kidney Cancer Drug Test after Early Success - Article from Reuters. - September 7, 2017

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Importance of Glomerular Filtration Rate Change As Surrogate Endpoint for the Future Incidence of End-Stage Renal Disease in General Japanese Population: Community-Based Cohort Study - Free, Open Access, First Online article from Clinical and Experimental Nephrology. - September 7, 2017

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Can Augmented are in CKD Stages 4-5 Change the Path to ESRD? - Article from Nephrology News & Issues. - September 6, 2017

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Effectiveness of Quality Improvement Strategies for the Management of CKD — A Meta-Analysis - CJASN Express abstract. - September 6, 2017

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Glomerular Filtration Rate and Initiation of Dialysis - Early View abstract from Therapeutic Apheresis and Dialysis. - September 6, 2017

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Kidney Disease Is Linked to Higher Risk for Atrial Fibrillation - (Registration required, but free.) Commentary from Medscape Nephrology. - September 6, 2017

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Sodium MRI: a New Frontier in Imaging in Nephrology - Published Ahead-of-Print Abstract from Current Opinion in Nephrology and Hypertension. - September 5, 2017

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Prediction Models for the Mortality Risk in Chronic Dialysis Patients: a Systematic Review and Independent External Validation Study - Abstract and link to full-text PDF from Clinical Epidemiology. - September 5, 2017

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Association Between More Intensive vs Less Intensive Blood Pressure Lowering and Risk of Mortality in Chronic Kidney Disease Stages 3 to 5 — A Systematic Review and Meta-analysis - New Online abstract and editorial extract from JAMA Internal Medicine. - September 5, 2017

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Protein Shown to be Predictor of Kidney Damage in Children - Press release from Rush University Medical Center. - September 5, 2017

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Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial - Latest Article abstract from Annals of Internal Medicine. - September 5, 2017

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Use of the RenalGuard System to Prevent Contrast-Induced AKI: A Meta-Analysis - Early View abstract from Journal of Interventional Cardiology. - September 4, 2017

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Projecting Prevalence, Costs and Evaluating Simulated Interventions for Diabetic End Stage Renal Disease in a Canadian Population of Aboriginal and Non-Aboriginal People: an Agent Based Approach - Free, Open Access Article from BMC Nephrology. - September 4, 2017

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Statistical Methods for Modeling Time-Updated Exposures in Cohort Studies of Chronic Kidney Disease - CJASN Express Abstract. - August 2017

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Biomarkers in Acute Kidney Injury and Beyond - Article from ASN's Kidney News Online. - August 2017

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Updates from The Lancet  Kidney Campaign - August 2017

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Intravenous Drug Users Who Require Dialysis: Causes of Renal Failure and Outcomes - Free, Open Access, Advance Article from Clinical Kidney Journal. - August 31, 2017

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New Findings May Help Protect the Kidney Health of Individuals with Obesity - August 31, 2017

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Liraglutide and Renal Outcomes in Type 2 Diabetes - Abstract and editorial extract from The New England Journal of Medicine. Article from Renal & Urology News. - August 31, 2017

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Guidelines for Treatment of Renal Injury during Cancer Chemotherapy 2016 - Free, Open Access, First Online article from Clinical and Experimental Nephrology. - August 30, 2017

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Obesity and Synergistic Risk Factors for Chronic Kidney Disease in African American Adults: the Jackson Heart Study - Advance Article abstract from NDT. - August 30, 2017

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Researchers Discover MRI Can Measure Kidney Scarring and Predict Future Kidney Function - August 30, 2017

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Pooled Analysis of Phase III Trials Indicate Contrasting Influences of Renal Function on Blood Pressure, Body Weight, and HbA1c Reductions with Empagliflozin - Article in Press abstract from Kidney International. - August 30, 2017

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Free, Open Access Articles from BMC Nephrology - August 29, 2017

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Article in Press Abstracts and Full-Text PDFs from Kidney International Reports - August 29, 2017

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Marijuana Won't Harm Healthy Young People's Kidneys, Study Suggests - Article from HealthDay. Press release and CJASN Express abstract from the American Society of Nephrology. - August 24, 2017

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Cancer Drug May Benefit Patients with Inherited Form of Kidney Disease - August 24, 2017

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Association of Serum Albumin Levels with Kidney Function Decline and Incident Chronic Kidney Disease in Elders - Advance Article Abstract from NDT. - August 23, 2017

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Infographic: Polycystic Kidney Disease (PKD) - Resource from the Mayo Clinic. - August 23, 2017

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Prenatal Growth and CKD in Older Adults: Longitudinal Findings From the Helsinki Birth Cohort Study, 1924-1944 - Articles in Press Abstract from American Journal of Kidney Diseases. - August 22, 2017

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Life Expectancy for Patients from the Southeastern United States with IgA Nephropathy - 20-page pdf - Article in Press Abstract and Full-Text PDF from Kidney International Reports. - August 22, 2017

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Intensive Hemodialysis Using PMMA Dialyzer Does Not Increase Renal Response Rate in Multiple Myeloma Patients with Acute Kidney Injury - Free, full-text, Advance Article from Clinical Kidney Journal. - August 22, 2017

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Kidney Failure Deaths Move Filmmaker to Raise Research Funds - (Registration required, but free.) Article from Medscape Nephrology. - August 18, 2017

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Surge of Kidney Failure Deaths Blamed on Heat Exposure - (Registration required, but free.) Article from Medscape Medical News. - August 18, 2017

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A Survey of Canadian Nephrologists Assessing Prognostication in End-Stage Renal Disease - Free, full-text, Open Access article from Canadian Journal of Kidney Health and Disease. - August 18, 2017

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Study of California Kidney Cancer Shows Declining Incidence, End of a Trend - August 18, 2017

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The United States Can Reduce Socioeconomic Disparities By Focusing On Chronic Diseases - Posting from the Health Affairs Blog. - August 17, 2017

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Association between Periodontal Disease and Mortality in People with CKD: a Meta-Analysis of Cohort Studies - Free, Open Access article from BMC Nephrology. - August 16, 2017

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Number Of Dialysis Patients In California Surges - Article from California Healthline. - August 15, 2017

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Reducing Nephrotoxicity in Cancer Patients Undergoing CT Scans - Article from Medscape Nephrology (registration required, but free). - August 15, 2017

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Effect of Tolvaptan on Renal Handling of Water and Sodium, GFR and Central Hemodynamics in Autosomal Dominant Polycystic Kidney Disease during Inhibition of the Nitric Oxide System: a Randomized, Placebo-Controlled, Double Blind, Crossover Study - Free, Open Access article from BMC Nephrology. - August 15, 2017

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Keeping a Promise to Patients with Failing Kidneys - Article from Duke University School of Medicine. - August 14, 2017

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Relationship of Kidney Injury Biomarkers with Long-Term Cardiovascular Outcomes after Cardiac Surgery - JASN Express abstract. - August 14, 2017

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Receipt of Nephrology Care and Clinical Outcomes Among Veterans With Advanced CKD - Article in Press Abstract from American Journal Of Kidney Diseases. - August 12, 2017

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The Nature, Consequences, and Management of Neurological Disorders in Chronic Kidney Disease - Early View Abstract from Hemodialysis International. - August 11, 2017

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Drug Treatments Didn't Work. Can a Simple Diet Help Change These Children's Lives? - Article From STAT. The children at this Florida camp are living with a rare kidney disorder called focal segmental glomerulosclerosis. - August 9, 2017

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Clinical Outcomes and Survival in Pediatric Patients Initiating Chronic Dialysis: a Report of the NAPRTCS Registry - First Online abstract from Pediatric Nephrology. - July 31, 2017

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005
Better Chronic Disease Care program from California Healthcare Foundation

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

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Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
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ERA-EDTA Registry Annual Report (covers 2015 data) - (150-page pdf) The ERA-EDTA Registry collects data on renal replacement therapy (RRT) via the national and regional renal registries in Europe and countries bordering the Mediterranean Sea. For this 2015 Annual Report data sets from 52 national or regional renal registries in 36 countries were used.

2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
blue ball New Infographic: Polycystic kidney disease (PKD) from the Mayo Clinic News Network
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
Safe Kidney Care web site+
10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

K/ DOQI Main Page on the National Kidney Foundation web site
K/DOQI Guidelines: Clinical guidelines for when to initiate dialysis
 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2016 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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