RenalWEB Home Page
Last Updated 10/21/18

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Free, Full-Text Articles from American Journal Of Kidney Diseases - November 2018

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Chronic Kidney Diseases in Agricultural Communities: A Discussion with NIEHS and NIDDK - Feature from Kidney News Online. - October/November 2018

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Free, Full-Text, Accepted Articles from Nephrology - October 2018

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New UK Guidelines: Renal Replacement Therapy and Conservative Management - Flowchart and quality standard from the National Institute for Health and Care Excellence (NICE). Press release via Pharmafield. - October 2018

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Translational Methods in Nephrology: Individual Treatment Effect Modeling - Free, full-text, Published Ahead of Print article from the Journal of the American Society of Nephrology. - October 2018

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BMI Is Associated with the Development of Chronic Kidney Diseases in Hypertensive Patients with Normal Renal Function - Abstract from Journal of Hypertension. - October 2018

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Experiences with Doctors and Hospitalization Risk in Hispanic Kidney Disease Patients - Press release and Published Ahead of Print CJASN abstract from the American Society of Nephrology. - October 18, 2018

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Don't Be Alarmed, but Your Kidney Has a Clock - Posting from the Renal Fellow Network blog. - October 18, 2018

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A New Test Published in AACC's Clinical Chemistry Journal Could Help Prevent Kidney Failure in Diabetic Patients - Press release from the American Association for Clinical Chemistry. - October 18, 2018

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Pay Attention to Kidney Disease Risk in People Living with HIV - Article from Internal Medicine News. - October 18, 2018

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Contrast and AKI: The Plot Thickens - Posting from the Renal Fellow Network blog. - October 18, 2018

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Study: Even Low Levels of Arsenic Can Cause Kidney Disease - Press release from Texas Tech University. - October 17, 2018

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CKD in Patients with Bilateral Oophorectomy - Published Ahead of Print CJASN abstract. - October 17, 2018

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Heart Rate Variability as a Predictor of Rapid Renal Function Deterioration in Chronic Kidney Disease Patients - Accepted Article abstract from Nephrology. - October 17, 2018

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The Renal Safety of L-Carnitine, L-Arginine, and Glutamine in Athletes and Bodybuilders - Article in Press abstract from Journal of Renal Nutrition. - October 16, 2018

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Success! New Kidney Disease Funding - Posting from the NKF Advocacy in Action blog. - October 15, 2018

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Predicting Kidney Failure Risk after Acute Kidney Injury among People Receiving Nephrology Clinic Care - Free, full-text, Advance Article from NDT. - October 15, 2018

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Free, Open Access articles from Canadian Journal of Kidney Health and Disease - October 15, 2018

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Obesity and Risk of End-Stage Renal Disease in Patients with Chronic Kidney Disease: a Cohort Study - Advance Article abstract from The American Journal of Clinical Nutrition. - October 13, 2018

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Common Clinical Markers Predict End-Stage Renal Disease in Children with Obstructive Uropathy - First Online abstract from Pediatric Nephrology. - October 13, 2018

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University of Calgary Researchers Discover Ways to Protect Kidneys during Imaging Tests - Article from The Star Calgary. - October 12, 2018

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Advance Article Abstracts from NDT - October 12, 2018

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Updated Canadian Expert Consensus on Assessing Risk of Disease Progression and Pharmacological Management of Autosomal Dominant Polycystic Kidney Disease - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - October 12, 2018

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Saliva Urea Nitrogen Dipstick - October 12, 2018

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Articles in Press Abstracts from American Journal of Kidney Diseases - October 11, 2018

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Researchers Call for Reform of Medicare Payments for Chronic Kidney Disease Patients - News release from the National Kidney Foundation. Free, full-text, Published Ahead of Print article from the Journal of the American Society of Nephrology. - October 11, 2018

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Free, Open Access Articles from BMC Nephrology - October 11, 2018

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Is Kidney Dialysis Always Needed When Septic Shock Strikes? - Article from HealthDay. Abstract from The New England Journal of Medicine. - October 10, 2018

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Treatment of Calciphylaxis in Chronic Kidney Disease: A Systematic Review and Meta-Analysis - (59-page PDF) - Articles in Press Abstract and Full-Text PDFs from Kidney International Reports. - October 9, 2018

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Association of Thyroid Status Prior to Transition to End-Stage Renal Disease with Early Dialysis Mortality - Advance Article from NDT. - October 8, 2018

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Gout Drug May Protect against Chronic Kidney Disease - Press release from Boston University School of Medicine. Article from HealthDay. Free, full-text, New Online article from JAMA Internal Medicine. - October 8, 2018

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Severe Acute Kidney Injury and Multiple Organ Failure in a 17-Day-Old Newborn: When Pathology Makes the Difference - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - October 8, 2018

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Online First Abstracts from Blood Purification - October 5-8, 2018

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UN High-Level Meeting 2018: Targeted Action on Kidney Disease - Posting from the ISN-Blog. - October 5, 2018

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The Efficacy of Low Protein Diets in Delaying the Need for Maintenance Dialysis - News brief from the European Nephrology Portal. Abstract from Cochrane Reviews. - October 4, 2018

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High Blood Levels of Inflammatory Marker Linked with Kidney Function Decline in Adults - Press release and JASN Published Ahead of Print abstract from the American Society of Nephrology. - October 4, 2018

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Acute Kidney Injury among Hospitalized Children in China - CJASN Published Ahead of Print abstract. - October 3, 2018

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Impact of Introducing Electronic Acute Kidney Injury Alerts in Primary Care - Free, full-text, Advance Article from Clinical Kidney Journal. - October 3, 2018

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#KidneyX, in an Effort To Spur #innovation, Covers the Entire Spectrum of Kidney Care: Prevention, Diagnostics, and Treatment Tweet from @KidneyX. - October 3, 2018

Editor's note: Unfortunately, KidneyX does not recognize the necessity of renal rehabilitation. The current systems of care fail to acknowledge dialysis patients' goals. Much more is needed than improvements in technology.

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Press Releases from Diabetologia - October 3, 2018

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Tissue Engineering Is No Quick Fix for Kidney Disease, but Early Intervention Can Help - Article from Horizon magazine. - October 2, 2018

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Chronic Kidney Disease Outcomes Can Be Improved by Expanding Specialist Care - Press release from Rand Corporation. Free, full-text, Published Ahead of Print article from the Journal of the American Society of Nephrology. - October 2, 2018

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USC Biomedical Engineers Awarded $2.4 Million to Combat Kidney Disease - Article from Los Angeles Business Journal. - October 2, 2018

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Research Brief: Primary Care Strategies to Improve Health of Chronic Disease Patients - Press release from the University of Minnesota. - October 2, 2018

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Articles in Press Abstracts from American Journal Of Kidney Diseases - October 2, 2018

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Articles from Healio - October 1-3, 2018

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October 2018 Issue of Clinical Kidney Journal - 20 free, full-text articles. - October 1, 2018

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Genetic Variants Reveal New Targets for Chronic Kidney Disease Treatment - Press release from University of Pennsylvania School of Medicine. - October 1, 2018

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Inflammation in Diabetic Kidney Disease - Free, full-text, Online First mini-review from Nephron. - October 1, 2018

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Free, Full-Text Articles from September 2018 Issue of Advances in Chronic Kidney Disease - September 2018

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Kidney Function Reserve Capacity in Early and Later Stage Autosomal Dominant Polycystic Kidney Disease - CJASN Express abstract. - September 2018

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Hereditary Kidney Disease: All Family Members Are Affected - Free, full-text article from the Journal of the American Society of Nephrology. - September 28, 2018

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End-Stage Kidney Disease following Surgical Management of Kidney Cancer - CJASN Express abstract. - September 28, 2018

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Vitamin B Supplements May Protect Kidney Function in Children with Diabetes - Press release from the European Society for Pediatric Endocrinology. - September 28, 2018

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2019 World Kidney Day Theme - Kidney Health for Everyone Everywhere.

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Kidney Disease Biomarker May Also Be a Marker for COPD - Press release from the American Thoracic Society. - September 28, 2018

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The Future: Experimental Therapies for Renal Disease in Diabetes - Free, full-text, Online First minireview from Nephron. - September 26, 2018

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On the Trail of a Deadly Disease That Cuts Down Farmworkers in Their Prime - Article from Bloomberg Quint. - September 26, 2018

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Homelessness and Kidney Disease - Posting from the Renal Fellow Network blog. - September 25, 2018

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Nephrology Journal Club PKD1/PKD2 Complex Video Summary - 10-minute YouTube video on a recent Nephrology Journal Club discussion #NephJC. - September 21, 2018

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Renal Genetics in Australia: Kidney Medicine in the Genomic Age - Accepted Article abstract and full-text (26-page PDF) from Nephrology. - September 21, 2018

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Does Metformin Increase the Risk for Lactic Acidosis in CKD? - (Registration required, but free.) Viewpoint article from Medscape Nephrology. - September 21, 2018

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Comment from Miriam Lippel Blum on Dialysis Patient Survival - Comment made to the "What are survival rates for dialysis patients?" posting on the Renal Fellow Network blog. - September 20, 2018

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Free, Open Access Articles from PLOS ONE - September 13 - October 4, 2018

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Circadian Rhythms and the Kidney - Abstract from Nature Reviews Nephrology. - August 24, 2018

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

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Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

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Clinical Pharmacokinetics in Kidney Disease — Fundamental Principles - Free, Full-Text, CJASN Express Articles - June 2018

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
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ERA-EDTA Registry Annual Report (covers 2015 data) - (150-page pdf) The ERA-EDTA Registry collects data on renal replacement therapy (RRT) via the national and regional renal registries in Europe and countries bordering the Mediterranean Sea. For this 2015 Annual Report data sets from 52 national or regional renal registries in 36 countries were used.

2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
blue ball Infographic: Polycystic kidney disease (PKD) from the Mayo Clinic News Network
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
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Mayo Clinic Minute: Understanding Chronic Kidney Disease - 1-minute video.

blue ball Mayo Clinic Q and A: Understanding chronic kidney disease from the Mayo Clinic web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
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Renal Disorders in Pregnancy: Core Curriculum 2019 - Free, full-text, Article in Press from American Journal of Kidney Diseases. - August 16, 2018

10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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UK's "Think Kidneys" Campaign - 2018

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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

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K/ DOQI Main Page on the National Kidney Foundation web site

 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

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Eleven New Indicators of CKD Have Been Added to the Resources on the CDC's CKD Surveillance System Website - April 2018

View all indicators.

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2017 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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