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Last Updated 06/18/17

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Free, Full-Text Articles from NDT - June 2017

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Free, Full-Text, June 2017 Issue of Clinical Kidney Journal. Articles Include - June 2017

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Dialysis Requirement and Long-Term Major Adverse Cardiovascular Events in Patients with Chronic Kidney Disease and Superimposed Acute Kidney Injury - Abstract from Nephron. - June 2017

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The China Kidney Disease Network (CK-NET): "Big Data—Big Dreams" - Free, Full-Text Article from American Journal Of Kidney Diseases. - June 2017

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Symptom Experience in Non-Dialysis-Dependent Chronic Kidney Disease: a Qualitative Descriptive Study - Early View Abstract from Journal of Renal Care. - June 14, 2017

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A New Mutation in Kidney Disease - Press release from Osaka University. - June 14, 2017

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Dialysis in the Undocumented: the Past, the Present, and What Lies Ahead - Early View Abstract from Seminars In Dialysis. - June 13, 2017

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35th Vicenza Course on AKI & CRRT — Vicenza, June 13–16, 2017 - 27-page pdf from Blood Purification. - June 13, 2017

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Acute Kidney Injury: Emerging Pharmacotherapies in Current Clinical Trials - First Online abstract from Pediatric Nephrology. - June 10, 2017

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Quantity Over Quality? Minorities Shown To Get An Excess Of Ineffective Care - Article from Kaiser Health News. Abstract from Health Affairs. - June 9, 2017

Editor's note: Doesn't this concept make up a big part of the basic playbook that is used in for-profit dialysis care?

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Kidney Disease Awareness: Valuable Resources for Providers and Patients - (Registration required, but free.) Article from Medscape Nephrology. - June 8, 2017

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Articles from Nephrology News & Issues - June 7, 2017

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Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal - Free, full-text, Issue-in-Progress in-depth review from Blood Purification. Cappuccino with Claudio Ronco video. - June 7, 2017

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One in Seven American Adults Estimated to Have Chronic Kidney Disease - Press release from the National Kidney Foundation. - June 6, 2017

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HIV-Infected Living Kidney Donors Have Low ESRD Risk - Article from Renal & Urology News. - June 6, 2017

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Blue Cross and Blue Shield of Texas to Launch $10-million Statewide Initiative to Help Fight Chronic Diabetic Kidney Disease and Chronic Obstructive Pulmonary Disease - Press release. - June 5, 2017

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Explaining Trends and Variation in Timing of Dialysis Initiation in the United States - Free full-text article from Medicine. Article from Nephrology News & Issues. - June 5, 2017

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eGFR Level Alone May Tell Little about True Timing of Dialysis Initiation - Press Release from Arbor Research. - June 2, 2017

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Association of Intensive Blood Pressure Control and Kidney Disease Progression in Nondiabetic Patients With Chronic Kidney Disease — A Systematic Review and Meta-analysis - Abstract from JAMA Internal Medicine. - June 1, 2017

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Diabetes with Early Kidney Involvement May Shorten Life Expectancy by 16 Years - Article in Press abstract from Kidney International. - June 1, 2017

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Dialysis Initiation in Patients with Poor Prognosis: An Opportunity to Reflect - Posting from the AJKD blog. - June 1, 2017

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Articles from Medscape Nephrology (registration required, but free) - June 1, 2017

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Renal Failure Deaths and Their Risk Factors in India 2001-13: Nationally Representative Estimates from the Million Death Study - Free, full-text article, letter to the editor, and authors' reply from The Lancet Global Health. - May 2017

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Abstracts from The Lancet - May 2017

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Intensive Versus Minimal Standard Dosage for Peritoneal Dialysis in Acute Kidney Injury: a Randomized Pilot Study - PDI in Press Abstract. - May 2017

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Baxter and Mayo Clinic Launch Research and Development Collaboration to Transform Patient Care - Press release. - May 31, 2017

"The first project will focus on kidney disease, with additional projects planned in other areas."

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Skyrocketing Chronic Diseases Will Cause Major Healthcare Spending Spike - May 31, 2017

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"Dictatorship in Venezuela Eliminates Programs of Peritoneal Dialysis and Kidney Transplantation" - Tweet from Victor Sanna, pediatric nephrologist. - May 30, 2017

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Free, Open Access Articles from BMC Nephrology - May 30, 2017

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Reducing the Costs of Chronic Kidney Disease While Delivering Quality Health Care: a Call to Action - Advance Online abstract from Nature Reviews Nephrology. - May 30, 2017

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Life with One Kidney - Free, Open Access, First Online educational review from Pediatric Nephrology. - May 29, 2017

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Short-and Long-Term Outcomes after Nonsevere Acute Kidney Injury - First Online Abstract from Clinical and Experimental Nephrology. - May 29, 2017

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Incremental Dialysis: Can It Make a Difference for Residual Renal Function? - Article from Nephrology News & Issues. - May 26, 2017

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The Roles of Continuous Renal Replacement Therapy in Septic Acute Kidney Injury - Early View Abstract from Artificial Organs. - May 26, 2017

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"Chronic Kidney Disease Improvement in Research and Treatment Act" (HR. 2644) Introduced - News release from Kidney Care Partners. HR. 2644. - May 25, 2017

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The Good News and the Good News About the Treatment of Lupus Nephritis - Posting from the AJKD blog. - May 25, 2017

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Free, Open Access Articles from BMC Nephrology - May 25, 2017

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The Long and Winding Road: What We Think We Know About The Treatment of Proliferative Lupus Nephritis - Posting from the AJKD blog. - May 22, 2017

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Chronic Kidney Disease and Cataract: Seeing the Light - Free, full-text, Issue-in-Progress editorial and related abstract from American Journal of Nephrology. - May 20, 2017

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The Effect of War on Syrian Refugees with End-Stage Renal Disease - Full-Text PDF of Articles in Press from Kidney International Reports. - May 19, 2017

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Risk of Acute Kidney Injury and Survival in Patients Treated with Metformin: an Observational Cohort Study - Free, Open Access Article from BMC Nephrology. - May 19, 2017

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Doctor Uses His Phone To Diagnose Own Kidney Stone - April 26, 2017

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005
Better Chronic Disease Care program from California Healthcare Foundation

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

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Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Choosing the Right Treatment from Fresenius Medical Care/UltraCare web site
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
blue ball Chronic Kidney Disease from the American Kidney Fund web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
Safe Kidney Care web site
10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

K/ DOQI Main Page on the National Kidney Foundation web site
K/DOQI Guidelines: Clinical guidelines for when to initiate dialysis
 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2016 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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