RenalWEB Home Page
Last Updated 04/17/18

Chronic kidney disease (CKD) is permanent kidney damage due to injury or disease. More than 20 million Americans-one in nine adults-have chronic kidney disease, and most don't even know it. More than 20 million others are at increased risk.

How long you can live with CKD depends on your age, other health problems, and how involved you become in your care. Some people with early CKD never experience kidney failure. Others reach kidney failure (end-stage renal disease (ESRD)) and live for decades with dialysis or kidney transplants.

Simple tests in a doctor's office can detect chronic kidney disease in its early stages when lifestyle changes and medication can be prescribed to delay or prevent the progression of kidney disease and its complications. Left untreated, chronic kidney disease may ultimately lead to kidney failure and/or heart disease.

There are many risk factors that make having CKD more likely, with the leading risk factors being diabetes, hypertension, and a family history of CKD.

Warning: Changes should never be made in a patient's treatment or care based solely on the information found here.  All patients have unique healthcare concerns and considerations and these must all be taken into account before any changes can be safely made.  All medical and therapeutic decisions must come from a qualified health care provider.  Read RenalWEB's Legal Disclaimer before proceeding.

  NEWS and LATEST ARTICLES

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Eleven New Indicators of CKD Have Been Added to the Resources on the CDC's CKD Surveillance System Website - April 2018

View all indicators.
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Free, Full-Text, CJASN Express Articles - April 2018

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Free, Full-Text Articles from NDT - April 2018

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Survival in Children Requiring Chronic Renal Replacement Therapy - Free, Full-Text Article from Pediatric Nephrology. - April 2018

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Free, Full-Text Articles from Kidney International - April 2018

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Hydroxychloroquine Use and Risk of CKD in Patients with Rheumatoid Arthritis - CJASN Express abstract. - April 16, 2018

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Effect of Neprilysin Inhibition on Renal Function in Patients with Type 2 Diabetes and Chronic Heart Failure Who Are Receiving Target Doses of Inhibitors of the Renin-Angiotensin System: a Secondary Analysis of the PARADIGM-HF Trial - Online First abstract from The Lancet Diabetes and Endocrinology. - April 13, 2018

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KDIGO Announces Publication of The Advanced CKD Controversies Conference Report - News release from Kidney Disease: Improving Global Outcomes. - April 13, 2018

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Burden of Proof for Tolvaptan in ADPKD — Did REPRISE Provide the Answer? - Free, Full-Text, CJASN Express Article. - April 13, 2018

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CKD and ESRD in US Hispanics - Articles in Press Abstract from American Journal Of Kidney Diseases. - April 13, 2018

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What Is an "eGFR," and Why And When Does It Matter? - Posting from the KidneyViews blog. - April 12, 2018

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Improving the Prognosis of Patients with Severely Decreased Glomerular Filtration Rate (CKD G4 +): Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference - Free, Open Access, Article in Press from Kidney International. - April 12, 2018

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First Seeds of Kidney Cancer Sown in Adolescence - April 12, 2018

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Early Data Indicates Medicare Accountable Care Organizations Varied in Primary Care Management for Chronic Conditions - Press release and full-text article from Medical Care. - April 12, 2018

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Diversity of the Midstream Urine Microbiome in Adults with Chronic Kidney Disease - Free, Open Access, First Online article from International Urology and Nephrology. - April 12, 2018

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Protein Restriction Effective in Delaying Need for Dialysis, Comprehensive Study Shows - Press Release from the National Kidney Foundation Spring Clinical Meetings. - April 11, 2018

Tweets @NKFCLINICALS and #NKFClinicals.

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Psoriasis and Risk of Incident Chronic Kidney Disease and End-Stage Renal Disease: a Systematic Review and Meta-Analysis - First Online abstract from International Urology and Nephrology. - April 11, 2018

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A Call To Action on Kidney Disease: 2018 United Nations High-Level Meeting on Non-Communicable Diseases - Advocacy campaign from the International Society of Nephrology. - April 10, 2018

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Risk Stages Defined for Children with Chronic Kidney Disease - Press release from Children's Hospital of Philadelphia. Article in Press abstract from American Journal of Kidney Diseases. - April 10, 2018

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Haste Makes Waste — Should Current Guideline Recommendations for Initiation of Renal Replacement Therapy for Acute Kidney Injury Be Changed? - Early View abstract from Seminars in Dialysis. - April 10, 2018

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Using a Home Test Kit and Smartphone to Test for Kidney Disease - Press release from the National Kidney Foundation. - April 10, 2018

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Very Low-Protein Diet Can Delay the Need for Dialysis in Patients with Chronic Kidney Disease (CKD) - (2-page pdf) Press release from ERA-EDTA. Full-text article from Chronic Diseases and Translational Medicine. - April 9, 2018

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Dialysis Initiation and Mortality Among Older Veterans With Kidney Failure Treated in Medicare vs the Department of Veterans Affairs - Free, full-text, Online First article and editorial from JAMA Internal Medicine. - April 9, 2018

"Given the many unknown factors, the decision on when it is best to initiate dialysis should evoke humility. The goal should be to encourage thoughtful, joint decision making by nephrologists and their patients. The system should reinforce the careful weighing of pros and cons by supporting health care professionals in caring for patients with very low eGFR, and financial incentives should be realigned so that we do not inadvertently pressure patients to receive dialysis earlier than would be best for them."

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Acute Kidney Injury Changes with the Seasons - Free, full-text, Advance Article from NDT. - April 9, 2018

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Chronic Illnesses, Functional Limitations a Risk in Older Adults with Heart Failure - Press release from the American Geriatrics Society. - April 5, 2018

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Is It Safe to Hold Your Pee? Five Possible Complications - Article from Medical News Today. - April 5, 2018

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Delivering a "New Deal" of Kidney Health Opportunities to Improve Outcomes Within the Veterans Health Administration - Article in Press abstract from American Journal of Kidney Diseases. - April 4, 2018

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Nail in the Coffin for Fibroblast Growth Factor 23 as a Predictor of Kidney Function Decline - Free, full-text, Issue-in-Progress editorial and related abstract from American Journal of Nephrology. - April 3, 2018

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For Women with Kidney Cancer, Belly Fat Matters - April 3, 2018

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Can Increased Vigilance for Chronic Kidney Disease in Hospitalized Patients Decrease Late Referral and Improve Dialysis-Free Survival? - Free, Open Access Article from BMC Nephrology. - April 2, 2018

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Is Relative Overhydration Measurement by Bioimpedance Spectroscopy Useful in Reducing Morbidity and Mortality in Chronic Kidney Disease? - Free, full-text, Advance Article from Clinical Kidney Journal. - April 2, 2018

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Caffeine May Prevent Acute Kidney Injury in Preterm Neonates - Article from Renal & Urology News. - April 2, 2018

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Can Increased Vigilance for Chronic Kidney Disease in Hospitalized Patients Decrease Late Referral and Improve Dialysis-Free Survival? - Free, Open Access Article from BMC Nephrology. - April 2, 2018

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Free, Full-Text Articles in March 2018 Issue of Advances of Chronic Kidney Disease - March 2018

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OUTReach - Spring 2018 Issue - (8-page pdf) Publication of Reach Kidney Care. - March 2018

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Free, Full-Text Articles from Nephron - March 2018

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More Than One-Third of Male and Female Medicare Patients with Advanced Kidney Disease Are Not Seeing a Kidney Doctor before Developing Kidney Failure - Health consequence from the CDC's Chronic Kidney Disease Surveillance System. - March 2018

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Chimeric Antigen Receptor T Cell Therapy and the Kidney - Free, CJASN Express Article. - March 2018

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Potential Impact of Medicare Payment Policy on Misclassification of Dialysis-Requiring Acute Kidney Injury as ESRD: A National Temporal Trend Analysis - Free, full-text, Article in Press from American Journal of Kidney Diseases. - March 31, 2018

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Time-Centered Approach to Understanding Risk Factors for the Progression of CKD - CJASN Express abstract. - March 30, 2018

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Identification of Patients Expected to Benefit from Electronic Alerts for Acute Kidney Injury - CJASN Express Abstract. - March 29, 2018

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Diabetes Now Affects 23 Million U.S. Adults - Article from HealthDay  - March 29, 2018
Articles from the CDC's Morbidity and Mortality Weekly Report:

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Presenting the Kidney Collection Survey - News item from the International Society of Nephrology. - March 28, 2018

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Any Grade of Relative Overhydration Is Associated with Long-Term Mortality in Patients with Stages 4 and 5 Non-Dialysis Chronic Kidney Disease - Free, full-text, Advance Article from Clinical Kidney Journal. - March 28, 2018

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Mayo Clinic Minute: Understanding Chronic Kidney Disease - 1-minute video. - March 28, 2018

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Test for Antibiotic-Associated Kidney Damage in Children with Cystic Fibrosis Identified - March 28, 2018

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The U.S. Spends ~$34 Billion on ESRD Care per Year - Tweet from Sri Lekha Tummalapalli. - March 27, 2018

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Chimeric Antigen Receptor T Cell Therapy and the Kidney — What the Nephrologist Needs to Know - Free, full-text, CJASN Express article. - March 27, 2018

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ISN and SLANH Stand United on Venezuela's Kidney Health Crisis - News brief and full statement (2-page pdf) from the International Society of Nephrology. - March 26, 2018

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CKD Self-management: Phenotypes and Associations With Clinical Outcomes - Article in Press abstract from American Journal of Kidney Diseases. - March 26, 2018

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Perceived Benefits and Challenges of a Risk-Based Approach to Multidisciplinary Chronic Kidney Disease Care: A Qualitative Descriptive Study - Free, Open Access article from Canadian Journal of Kidney Health and Disease. - March 23, 2018

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Obesity Surgery Prevents Severe Chronic Kidney Disease and Kidney Failure - Press release from the University of Gothenburg. - March 22, 2018

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Advance Article Abstracts from NDT - March 22, 2018

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4 Lessons on Dealing with Teenage Kidney Disease - Posting from the Speak Now for Kids blog. - March 21, 2018

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Immunotherapy in Advanced Renal Cancer — Is Cure Possible? - March 21, 2018

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Telenephrology: Providing Healthcare to Remotely Located Patients with Chronic Kidney Disease - Issue-in-Progress abstract from American Journal of Nephrology. - March 20, 2018

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Coffee Consumption and Incident Kidney Disease: Results From the Atherosclerosis Risk in Communities (ARIC) Study - Article in Press abstract from American Journal of Kidney Diseases. - March 20, 2018

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Free, Open Access Articles from BMC Nephrology - March 20, 2018

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Value of Electronic Alerts for Acute Kidney Injury in High-Risk Wards: a Pilot Randomized Controlled Trial - Free, Open Access, First Online article from International Urology and Nephrology. - March 19, 2018

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Treatment Plans and Outcomes in Elderly Patients Reaching Advanced Chronic Kidney Disease - Free, full-text, Advance Article from NDT (author's video). - March 19, 2018

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The Truth about Women and Kidney Health - 27-minute YouTube video from the Kidney Foundation of Canada that provides basic information in a game show format. - March 18, 2018

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Postings from the Renal Fellow Network Blog - March 18, 2018

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Describing Pediatric Acute Kidney Injury in Children Admitted from the Emergency Department - First Online abstract from Pediatric Nephrology. - March 17, 2018

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Accelerating New Clinical Trials and Treatments for Kidney Disease - Press release from the National Kidney Foundation. - March 16, 2018

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Slightly Elevated Blood Sugar Tied to Heart and Kidney Problems - Article from Reuters. Online First abstract from The Lancet Diabetes & Endocrinology. - March 16, 2018

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Trends in Hospitalizations for Acute Kidney Injury — United States, 2000–2014 - Article from the CDC's Morbidity and Mortality Weekly Report. - March 16, 2018

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Study Addresses Barriers to Kidney Disease Screening among Black Americans - Press release and CJASN Express abstract from the American Society of Nephrology. - March 15, 2018

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Prevalence, Treatment Patterns, and Healthcare Resource Utilization in Medicare and Commercially Insured Non-Dialysis Dependent Chronic Kidney Disease Patients with and without Anemia in the United States - Free, Open Access article from BMC Nephrology. - March 15, 2018

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Diabetes: Are High Blood Glucose Levels an Effect Rather Than the Cause of the Disease? - Press release from the German Cancer Research Center. - March 15, 2018

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Delaying and Averting Dialysis Treatment: Patient Protection or Moral Hazard? - Free, full-text, Article in Press from American Journal of Kidney Diseases. - March 14, 2018

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Unfavorable Effects of History of Volume Overload and Late Referral to a Nephrologist on Mortality in Patients Initiating Dialysis: a Multicenter Prospective Cohort Study in Japan - Free, Open Access article from BMC Nephrology. - March 14, 2018

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Many Patients Show Signs of Chronic Kidney Disease before Diabetes Diagnosis - Press release from Veterans Affairs Research Communications. - March 14, 2018

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Chronic Disease Approaches Needed to Curb Gout's Growing Burden - Free, full-text, New Online article from the Journal of the American Medical Association. - March 14, 2018

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Assessing the Risk of CKD Progression Using Kidney Failure Risk Equations - Posting from the Renal Fellow Network blog. - March 13, 2018

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Free, Full-Text, Issue-In-Progress Articles from American Journal Of Nephrology - March 13, 2018

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Overcoming Translational Barriers in Acute Kidney Injury — A Report from an NIDDK Workshop - CJASN Express Abstract. - March 9, 2018

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Does Ramadan Fasting Affect Hydration Status and Kidney Function in CKD Patients? - Issue-in-Progress abstract from Annals of Nutrition & Metabolism. - March 8, 2018

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Latest USRDS Incident and Prevalent Counts by Quarter - Data from the United States Renal Data System. - January 2018

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Impacts and Outcomes of Kidney Research in Canada - (15-page pdf) Report by the Kidney Foundation of Canada. - 2017

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Renal Replacement Therapy for Children throughout the World: the Need for a Global Registry - Free, Open Access article from Pediatric Nephrology. - December 22, 2017

 
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  WEB RESOURCES

blue ball Latest Scientific Journal Articles on Chronic Kidney Disease
Kidney Beginnings: A Patient’s Guide to Living with Reduced Kidney Function - from the American Association of Kidney Patients (AAKP) web site
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Acute Kidney Injury (AKI) Patients - (1-page pdf) Medicare coverage summary and resources from Northwest Renal Network

About Chronic Kidney Disease (CKD) from The National Kidney Foundation web site
American Diabetes Association web site
Are You At Risk for Kidney Disease? from the American Kidney Fund web site
Barriers to successful care for chronic kidney disease (pdf) from BMC Nephrology - October 27, 2005

CDC's Chronic Kidney Disease Initiative - The CKD Initiative currently includes surveillance, epidemiology, and state-based demonstration projects and economic studies in collaboration with partners from other government agencies, universities, and national organizations.

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Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)
Chronic Kidney Disease from the American Association of Kidney Patients (AAKP) web site
Chronic Kidney Disease from the Hypertension, Dialysis, & Clinical Nephrology (HDCN) web site
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Chronic Kidney Disease patient page from the Journal of the American Medical Association. - May 24/31, 2016

blue ball Consensus Expert Recommendations for the Diagnosis and Management of Autosomal Recessive Polycystic Kidney Disease: Report of an International Conference (pdf) from the Journal of Pediatrics
blue ball Diabetic Kidney Disease - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
Education and Teaching Resources from the Royal Infirmary of Edinburgh Renal Unit web site
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ERA-EDTA Registry Annual Report (covers 2015 data) - (150-page pdf) The ERA-EDTA Registry collects data on renal replacement therapy (RRT) via the national and regional renal registries in Europe and countries bordering the Mediterranean Sea. For this 2015 Annual Report data sets from 52 national or regional renal registries in 36 countries were used.

2008 ESRD Briefing Book for State and Federal Policy Makers (pdf format requires Adobe Acrobat Reader) - from the ANNA web site
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Essentials of Chronic Kidney Disease - KidneyTalk podcast from Renal Support Network

blue ball Frequently Asked Questions About GFR Estimates (pdf) - from the National Kidney Foundation (NKF) web site
blue ball General Nephrology - this is a growing library of key high-impact articles in nephrology, chosen by UKidney's contributors as suggested reading for nephrology trainees and practitioners.
How to Have a Good Future with Kidney Disease a Life Options CKD Patient Education Toolkit - 2011
blue ball Infographic: Polycystic kidney disease (PKD) from the Mayo Clinic News Network
IgA nephropathy from the About web site
KEY - Kidney Education and You - free kidney education classes from the DaVita web site
Kidney Diseases from the National Institute of Health web site
Kidney Diseases Dictionary from the National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK) web site
Kidney Early Evaluation Program (KEEP) from the National Kidney Foundation (NKF) web site
Kidney Health Library from the Kidney & Urology Foundation of America (KUFA) web site
Life Options Rehabilitation Program Introduction to Chronic Kidney Disease
Living Well with Chronic Kidney Disease (pdf) from the American Kidney Fund (AKF) web site
blue ball Management of Acute Kidney Injury: Core Curriculum 2018 from the American Journal of Kidney Diseases
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new Mayo Clinic Minute: Understanding Chronic Kidney Disease - 1-minute video.

blue ball Mayo Clinic Q and A: Understanding chronic kidney disease from the Mayo Clinic web site
Medicare Coverage of Kidney Dialysis & Kidney Transplant Services (pdf) from the Medicare web site
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National Institute of Diabetes and Digestive Diseases (NIDDK) Publications in English and Spanish - July 2014

  • Chronic Kidney Disease and Medicines (Brochure) (EnglishSpanish)
  • Is My Child At Risk for Kidney Disease? (EnglishSpanish)
  • What I need to know about Kidney Failure and How It's Treated (EnglishSpanish)
National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
National Kidney Disease Education Program (NKDEP) from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) web site
Northwest Renal Network's Choosing a Treatment Type - 2-page pdf from the NW Renal Network - December 2012
Polycystic Kidney Disease (PKD) Educational Materials from the PKD Foundation web site
10 Steps for Protecting Kidney Health from the National Kidney Foundation (NKF) web site
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Understanding Kidney Disease (Four free book chapters) - resource from ISN Education- January 2016

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Updated UK Guideline: Chronic Kidney Disease – Early Identification and Management of Chronic Kidney Disease in Adults in Primary and Secondary Care - July 2014

Uremic Toxins: What Are They? An Integrated Overview of Pathobiology and Classification from the Journal of Renal Nutrition

Video on Failing Kidneys and Different Treatment Options - Posting from the Precious Bodily Fluids blog. - April 2015

What Is Your Kidney Score? from the National Kidney Foundation (NKF) web site
What You Can Do from the Life Options web site
When Your Child Has a Chronic Kidney Disease from the Nemours Foundation web site
 
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  ESSENTIALS AND CLASSICS

Chronic Kidney Disease: What Every Nurse Should Know - from the American Nephrology Nurses Association web site
  • Introduction to Chronic Kidney Disease: An Overview of Causes, Stages, and Treatment
  • Chronic Kidney Disease - Stages 1 through 3
  • Chronic Kidney Disease - Stages 4 and 5: Overview of Therapy Options
  • Kidney Replacement Therapy - Transplantation
  • Kidney Replacement Therapy - Self-Care Dialysis
  • Kidney Replacement Therapy - Assisted Dialysis
  • Chronic Kidney Disease in the Pediatric Population
Core Curriculum: Chronic Kidney Disease - full-text article from the American Journal of Kidney Diseases - January 2007
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Updated Guideline: VA/DoD Clinical Practice Guideline for the Management of Chronic Kidney Disease in Primary Care - Full-text from the National Guideline Clearinghouse. - December 2014

Indicators for Chronic Disease Surveillance (pdf) - article from Morbidity and Mortality Weekly Report (MMWR) - September 10, 2004
Screening, Monitoring, and Treatment of Early Stage Chronic Kidney Disease - recommendations from the American College of Physicians (October 2013)
Risk Factors for CKD from the Life Options web site
10 Symptoms of Kidney Disease from the Life Options web site
Frequently Asked Questions about CKD from the Life Options web site
Learn the Six Warning Signs of Kidney and Urinary Tract Disease from the National Kidney Foundation (NKF) web site
 
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  BEST CLINICAL PRACTICES

The National Kidney Foundation's Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - from the National Kidney Foundation (NKF)
Guidelines for Managing Kidney Disease from the Canadian Medical Association
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Evidence-based Clinical Practice Guidelines from Clinical and Experimental Nephrology - April 2016

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease (CKD5) - Free, full-text review article from Pediatric Nephrology. - September 2013

Testing for Chronic Kidney Disease: A Position Statement From the National Kidney Foundation - full-text article from the American Journal of Kidney Diseases - August 2007

Clinical Practice Recommendations for the Care of Infants with Stage 5 Chronic Kidney Disease - Free, full-text, Online First article from Pediatric Nephrology. - October 2012

Healthy People 2020 - National Institute of Health (NIH) guidelines for managing Chronic Kidney Disease
Elevated levels of serum creatinine: recommendations for management and referral - from the Canadian Medical Association - 1999
 
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  K/DOQI™ -  Kidney Disease Outcomes Quality Initiative

K/ DOQI Main Page on the National Kidney Foundation web site
K/DOQI Guidelines: Clinical guidelines for when to initiate dialysis
 


  KDIGO™ -  Kidney Disease Improving Global Outcomes ( pronounced "kay de go" )

Kidney Disease Improving Global Outcomes (KDIGO) web site

  PUBMED SEARCHES (National Library of Medicine's MEDLINE Database)

Kidney Diseases (General) from MEDLINEplus Health Information
chronic kidney disease Continually Updated!
chronic kidney disease AND risk factors Continually Updated!
MEDLINE / Pubmed Information from the National Library of Medicine
 

  PRODUCTS

 
 

  STATISTICS

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new Eleven New Indicators of CKD Have Been Added to the Resources on the CDC's CKD Surveillance System Website - April 2018

View all indicators.

The Chronic Kidney Disease (CKD) Surveillance System - from the Centers for Disease Control (CDC)

Fast Facts on Kidney Disease - Statistics from the National Kidney Foundation

Average Annual Health Care Use and Expenditures for Kidney Disease among Adults 18 and Older, U.S. Civilian Noninstitutionalized Population, 2003-2007 - Statistical brief (7-page pdf) from the Agency for Healthcare Research and Quality
Renal Data Extraction and Referencing (RenDER) System - new online data querying application accessible through the United States Renal Data System (USRDS) - USRDS Presentations & Posters, 2016 Researcher's Guide and the 2017 USRDS annual report - from the United States Renal Data System (USRDS) web site

2014 National Chronic Kidney Disease Fact Sheet - 3-page pdf. - from the Centers for Disease Control (CDC)

US Government Goals: Chronic Kidney Disease Chapter from the Healthy People 2020 Objectives
statehealthfacts.org - your source for state health data
 
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  UPCOMING EVENTS

NKF Health Screening Schedule - The National Kidney Foundation's (NKF) Kidney Early Evaluation Program (KEEP) is designed to identify those at risk for kidney disease - scroll down to view multiple screening dates and contact phone numbers.
The American Association of Kidney Patients (AAKP) Programs & Events
 
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  RELATED TOPICS

Dialysis Outcomes and Topics from the RenalWEB web site Continually Updated!
 
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  INPUT / SUGGESTIONS

E-mail to RenalWEB on the Chronic Kidney Disease Page
 
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